Table 3.
The information of 21 significantly differential metabolites.
| Name | VIP | Fold change | p-value | m/z | RT (s) | Quantitative analysis (Control) | Quantitative analysis (STC) |
|---|---|---|---|---|---|---|---|
| Thymine | 2.004 | 1.976↑ | 0.023 | 125.03524 | 74.3435 | 484,330 ± 612,626 | 956,822 ± 924,101 |
| Taurocholate | 1.305 | 0.101 | 0.043 | 514.28179 | 197.259 | 439,651 ± 1,041,027 | 44,580 ± 88,504 |
| Taurochenodeoxycholate | 2.909 | 0.167 | 0.017 | 498.28652 | 145.579 | 1,912,584 ± 3,520,092 | 319,093 ± 512,153 |
| Taurine | 2.025 | 0.314 | 0.007 | 124.00744 | 291.676 | 1,029,081 ± 1,142,722 | 323,370 ± 770,728 |
| Succinate | 3.916 | 0.199 | 0.015 | 117.01962 | 391.109 | 3,013,974 ± 5,118,610 | 598,775 ± 1,387,217 |
| Propionic acid | 2.522 | 0.209 | 0.013 | 73.03003 | 391.176 | 1,221,545 ± 1,999,220 | 255,230 ± 550,046 |
| Nervonic acid | 1.253 | 1.878↑ | 0.027 | 365.34001 | 37.606 | 83,699 ± 61,566 | 157,186 ± 166,513 |
| Glycyl-L-leucine | 1.566 | 0.597 | 0.039 | 187.10837 | 283.697 | 687,000 ± 554,262 | 410,403 ± 456,281 |
| Deoxycholic acid | 12.233 | 0.525 | 0.008 | 391.28427 | 128.334 | 30,298,350 ± 23,615,390 | 15,918,241 ± 16,317,735 |
| Cyclohexylsulfamate | 26.333 | 0.417 | 0.039 | 178.0543 | 70.444 | 212,951,579 ± 270,482,964 | 88,817,956 ± 175,614,185 |
| Cholic acid | 14.581 | 0.259 | 0.009 | 407.27861 | 218.452 | 30,438,945 ± 42,352,355 | 7,880,015 ±16,816,427 |
| Cholesteryl sulfate | 1.793 | 1.643↑ | 0.009 | 931.61153 | 26.4205 | 285,135 ± 209,642 | 46,8399 ± 306,055 |
| Chenodeoxycholate | 5.894 | 0.107 | 0.045 | 783.57383 | 128.579 | 4,318,477 ± 10,292,191 | 461,818 ± 717,881 |
| Arachidonic acid (peroxide free) | 1.986 | 0.504 | 0.024 | 303.23131 | 38.7865 | 2,093,885 ± 1,879,405 | 1,055,170 ± 1,580,409 |
| Adynerin | 4.451 | 0.426 | 0.002 | 515.30189 | 52.427 | 4,542,108 ± 3,782,549 | 1,932,674 ± 2,039,784 |
| 9,10-DiHOME | 2.347 | 0.436 | 0.002 | 313.23647 | 84.842 | 1,180,798 ± 1,006,075 | 514,772 ± 544,196 |
| 4-Pyridoxic acid | 1.901 | 1.679↑ | 0.002 | 182.04518 | 44.08 | 514,197 ± 249,711 | 863,303 ± 529,983 |
| 2-Methylbenzoic acid | 2.289 | 1.652↑ | 0.016 | 135.04488 | 129.02 | 635,109 ± 518,673 | 1,049,088 ± 747,583 |
| 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine | 2.270 | 0.558 | 0.014 | 452.27705 | 194.122 | 4,105,361 ± 3,615,908 | 2,289,623 ± 1,488,993 |
| 1-Methylxanthine | 1.211 | 0.583 | 0.028 | 165.04129 | 109.821 | 741,523 ± 618,759 | 432,025 ± 430,157 |
| 13(S)-HODE | 1.308 | 0.534 | 0.015 | 295.2263 | 47.747 | 1,205,164 ± 1,081,968 | 643,204 ± 569,528 |
Mass-to-charge ratio (m/z); retention time (RT); quantitative analysis: response strength, means ± SD.