Table 2.
Studies with the role of probiotics in the prevention of RID therapy for cervical cancer.
| Probiotics | Methods | Findings | Ref. |
|---|---|---|---|
| Lactobacillus acidophilus plus bifidobacterium bifidum | Patients who received cisplatin and pelvic radiotherapy were divided into a probiotic group and a placebo group. | Probiotics reduced the incidence of RID and improved stool consistency. | Chitapanarux et al., 2010 |
| Lactobacillus acidophilus LA-5 plus Bifidobacterium animalis subsp | Patients were randomized to a probiotics group (containing 75 billion live freeze-dried bacteria) or a placebo group. | Probiotics reduced the incidence of diarrhea and grade 2 abdominal pain. | Linn et al., 2019 |
| VSL#3 | Patients were assigned to either the high-potency probiotic preparation VSL#3 or placebo | Probiotic treatment reduces grade 3-4 diarrhea and reduces the number of bowel movements. | Delia et al., 2007 |
| Lactobacillus acidophilus LAC-361 and Bifidobacterium longum BB-536 | Patients were randomized between a placebo and either of two regiments of double strain Bifilact(®) probiotics. | Probiotics reduce radiation-induced grade 2-3-4 diarrhea. | Demers et al., 2014 |
| Lactobacillus casei DN-114 001 | Patients were randomly assigned to a probiotic drink or placebo. | Probiotic intervention had a significant effect on stool consistency. | Giralt et al., 2008 |