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. 2022 Jul 28;16:899772. doi: 10.3389/fnins.2022.899772

TABLE 6.

Experimental pain measures and physical performance measures.

Domains and variables Active group (n = 11)
Sham group (n = 10)
Baseline Post-intervention Baseline Post-intervention
Quantitative sensory testing measures
Vibration detection threshold
Symptomatic score/8 4.5 (1.4) 4.2 (1) 4.9 (1.6) 4.6 (1.5)
Asymptomatic score/8 4.4 (1.1) 4 (1) 5.2 (1.5) 4.7 (1.3)
Mechanical temporal summation
MTS-Symptomatic VAS change scores 16.8 (18.4) 15.8 (17.3) 7.9 (9.5) 13.6 (20)
MTS-Asymptomatic VAS change scores 11.2 (10.6) 14.9 (17.3) 6.3 (11.8) 12.6 (16.6)
MTS-Dorsal wrist VAS change scores 5.3 (9.8) 6.2 (5.3) 3.8 (9.3) 4.2 (6.7)
MTS-Tibialis anterior VAS change scores 12.4 (13.5) 17.7 (22) 7.1 (11.9) 11.7 (14.2)
Pressure pain threshold, M (SD)
PPT-Symptomatic (kPa) 232.9 (123.8) 254.8 (135.2) 291.9 (219.6) 354.7 (238.1)
PPT-Asymptomatic (kPa) 228.6 (103.6) 216 (104.8) 308.4 (213.5) 352.1 (261.9)
PPT-Dorsal wrist (kPa) 289.7 (170.3) 256.1 (115.6) 281.8 (137.6) 515.2 (673.1)
PPT-Tibialis anterior (kPa) 270.9 (96.3) 242.3 (116.6) 301.5 (181.8) 318.3 (159.2)
PPT-Thumb nail (kPa) 227.9 (71.3) 213.3 (89.3) 285.5 (167.6) 300.9 (192)
Cold hyperalgesia, M (SD)
PVAS-Symptomatic 52.3 (28.6) 35.2 (16.8) 32.7 (19.1) 27.7 (22.8)
PVAS-Asymptomatic 48.6 (29.6) 34.5 (14.8) 31.2 (18.8) 28.9 (20.6)
Conditioned pain modulation, M (SD)
CPM30 s % change scores (PPT-P4 at 30 s—PPT-p4 preconditioning score) 14 (40.1) 13.9 (17.1) 13.2 (28.4) 27.4 (32.2)
CPM60 s % change scores (PPT-P4 at 60 s—PPT-p4 preconditioning score) 20.3 (41.4) 6.8 (21.5) −14.5 (21.7) 25.1 (31)
CPM90 s % change scores (PPT-P4 at 90 s—PPT-p4 preconditioning score) 22.7 (40.9) 7.4 (11.5) −0.8 (21) 17.9 (26.1)
Tactile acuity and motor imagery performance
Body schema integrity, M (SD)
Time (seconds)
Left 2.1 (0.5) 2.3 (0.4) 2.4 (0.4) 2.1 (0.3)
Right 2.4 (0.6) 2.3 (0.4) 2.3 (0.4) 2.2 (0.4)
Accuracy (percentage)
Left 65.8 (11.7) 74.2 (9.6) 71.3 (16.6) 70.3 (10.9)
Right 72.7 (13.2) 73 (9.2) 70 (15.3) 72.7 (8.3)
Two-point discrimination (cm), M (SD)
Symptomatic 4.7 (2) 3.8 (1.3) 5.5 (2) 5.1 (1.3)
Asymptomatic 4.2 (1.8) 3.6 (1) 3.8 (1.8) 4.4 (1.3)
Sensitivity to physical activity
Discomfort (Peak discomfort-baseline) 3.6 (2.5) 2.9 (2.6) 2.4 (2.3) 1.7 (1.8)
Distance in meters 454.3 (131.4) 425.5 (131.2) 446 (60.3) 445.4 (116.9)
Physical performamce-30 s chair stand, M (SD) 9.5 (2.7) 10.5 (3.4) 11.1 (2.7) 12.7 (3.6)