Table I.
List of analysed histopathological criteria
| Epidermal changes | Dermal changes |
|---|---|
| Hyperkeratosis | Colloid bodies |
| Cornified layer compact | Vacuoles basal membrane zone |
| Parakeratosis, quantitative | Follicular involvement |
| Parakeratosis quality | Sweat gland involvement |
| – confluent | Inflammation |
| – staggered | – Superficial perivascular |
| – focal | – Deep perivascular |
| Neutrophils in cornified layer | – Interstitial |
| Pustules | – Band-like |
| – Intracorneal | – Lymphocytes |
| – Subcorneal | – Neutrophils |
| – Stratum spinosum | – Eosinophils |
| Bacterial colonization | – Plasma cells |
| Hyphae or spores | – Macrophages |
| Scale-crusts | – Melanophages |
| Stratum granulosum | – Siderophages |
| – Focal | – Erythrocyte extravasation |
| – Confluent | Blood vessels |
| Epidermal hyperplasia, quantitative | – Dilated, overall |
| Epidermal hyperplasia quality | – Dilated capillaries in dermal papillae |
| – Regular | – Vessels with close contact to basal |
| – Irregular | keratinocytes (“kissing vessels”) |
| – Regular and irregular, alternating | Increased number of vessels |
| Club-shaped rete ridges | – Papillary dermis |
| Thin rete ridges | – Reticular dermis |
| Suprapapillary thinning | Thick walled vessels: |
| Mitoses basal | – Papillary dermis |
| Mitoses suprabasal | – Reticular dermis |
| Spongiosis | – Subcutis |
| – Focal (suprapapillary) | Lipodermatosclerosis |
| – Confluent (suprapapillary and within rete ridges) | Papillary oedema |
| Fibrosis | |
| Intraepidermal inflammatory cells, overall | – Papillary dermis “vertical streaks” |
| – Reticular dermis | |
| Intraepidermal lymphocytes | – Subcutis |
| Intraepidermal neutrophils | |
| Intraepidermal eosinophils | |
| Neutrophilic spongiosis | |
| Eosinophilic spongiosis | |
| Necrotic keratinocytes | |
| – Stratum basale | |
| – Suprabasal | |
| Intraepidermal erythrocytes |