Table V.
Immunohistochemical analysis of psoriasis on the trunk (PT), psoriasis on the leg (PL) and stasis dermatitis (StD)
| PT (n = 8) Mean ± SD | PL (n = 8) Mean ± SD | StD (n = 8) Mean ± SD | PT vs PL (p-value) | PL vs StD (p-value) | |
|---|---|---|---|---|---|
| Ki-67a | 22.06 ± 17.96 | 30.81 ± 15.10 | 9.19 ± 7.77 | 0.28 | 0.010 |
| Bcl-2a | 4.63 ± 2.39 | 1.94 ± 1.61 | 5.94 ± 5.74 | 0.035 | 0.08 |
| CK 16 (distribution)b | 3.00 ± 0.00 | 2.75 ± 0.71 | 2.50 ± 0.93 | 1.00 | 0.72 |
| CK 16 (expression ratio)c | 1.29 ± 0.12 | 1.34 ± 0.13 | 1.25 ± 0.38 | 0.38 | 0.015 |
| CK 10 (distribution)b | 2.50 ± 0.93 | 2.25 ± 1.04 | 2.75 ± 0.71 | 1.00 | 0.57 |
| CK 10 (expression ratio)c | 1.16 ± 0.08 | 1.70 ± 0.72 | 2.03 ± 0.88 | 0.002 | 0.234 |
| S100A7d | 2.06 ± 0.78 | 2.75 ± 0.71 | 1.50 ± 0.46 | 0.041 | 0.005 |
| MPO (stratum corneum)e | 1.25 ± 0.71 | 1.63 ± 1.19 | 0.25 ± 0.38 | 0.61 | 0.009 |
| MPO (stratum granulosum/spinosum/basale)e | 0.63 ± 1.03 | 0.75 ± 1.04 | 0.25 ± 0.46 | 0.82 | 0.45 |
| MPO (dermis)e | 1.38 ± 0.74 | 0.94 ± 0.18 | 1.38 ± 0.74 | 0.27 | 0.24 |
| CD3 (stratum corneum)e | 0.00 ± 0.00 | 1.13 ± 0.35 | 0.00 ± 0.00 | 1.00 | 1.00 |
| CD3 (stratum granulosum/spinosum/basale)e | 0.75 ± 0.46 | 0.75 ± 0.46 | 0.88 ± 0.79 | 1.00 | 0.73 |
| CD3 (dermis)e | 2.88 ± 0.35 | 2.63 ± 0.74 | 2.69 ± 0.59 | 0.73 | 1.00 |
a
Number of positive nuclei per mm in keratinocytes of the basal and supra-basal layer.
b
Semi-quantitative 3-point score: 0=absent; 1=patchy; 2=continuous.
c
Ratio of the total thickness of the epidermis in a rete ridge divided by the thickness of the positive stained area.
d
Semi-quantitative 4-point score: 0=absent; 1=weak, only cytoplasmatic; 2=moderate, cytoplasmatic and few positive nuclei, 3=strong, cytoplasmatic and abundant nuclear positivity.
e
Semi-quantitative 3-point scale: 0=absent, 1=few present, 2=moderate present, 3=abundant present.
Bold indicates statistically significant p < 0.05. SD: standard deviation.