Table 2.

Multivariable model (adjusted odds ratios) for factors associated with treatment resistant depression within one year from index date for the incident study cohort (patients with the start of any major depressive disorder episode within the study period, 1/1/2016–31/5/2018), n = 2553

		Adjusted OR	95% CI		P-value
			Lower	Upper
Age	per year	1.014	1.006	1.021	< 0.001
Sex	Female vs. Male	0.889	0.736	1.074	0.222
Socio-economic status	Low (ref.)
	Medium	0.893	0.684	1.166	0.406
	High	0.939	0.754	1.169	0.572
District	Centre (ref.)
	North	0.695	0.543	0.889	0.004
	South	0.758	0.535	1.074	0.119
Personality disorder	Yes vs. no	1.706	1.201	2.424	0.003

CI confidence intervals