Table 1.
Diary variables in the study phases for patients and controls
| Interictal photophobia | Ictal photophobia | Headache frequency | Headache severity | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | P-value (FDR-corr.)a | Mean (SD) | P-value (FDR-corr.)a | Mean (SD) | P-value (FDR-corr.)a | Mean (SD) | P-value (FDR-corr.)a | ||
| Baseline | Patients (N = 10) | 2.59 (1.82) | 0.002 | 2.85 (2.85) | 0.012 | 0.12 (0.09) | 0.025 | 1.15 (0.88) | 0.023 |
| Controls (N = 10) | 0.06 (0.18) | 0.00 (0.00) | 0.01 (0.05) | 0.00 (0.00) | |||||
| Total (N = 20) | 1.32 (1.81) | 1.43 (2.45) | 0.07 (0.09) | 0.58 (0.85) | |||||
| Flash | Patients (N = 10) | 2.53b (1.50) | 0.002 | 2.02 (2.56) | 0.079 | 0.24 (0.31) | 0.190 | 0.71 (0.78) | 0.247 |
| Controls (N = 10) | 0.01 (0.05) | 0.00 (0.00) | 0.06 (0.14) | 0.23 (0.50) | |||||
| Total (N = 20) | 1.27 (1.65) | 1.01 (2.04) | 0.15 (0.25) | 0.47 (0.68) | |||||
| Post Flash | Patients (N = 10) | 1.67 (1.06) | 0.002 | 2.75 (2.42) | 0.012 | 0.18 (0.12) | 0.013 | 1.45 (0.96) | 0.023 |
| Controls (N = 10) | 0.00 (0.00) | 0.00 (0.00) | 0.02 (0.05) | 0.20 (0.63) | |||||
| Total (N = 20) | 0.83 (1.12) | 1.38 (2.18) | 0.10 (0.12) | 0.83 (1.02) | |||||
| Dark | Patients (N = 10) | 1.73 (1.47) | 0.007 | 3.11 (2.39) | 0.012 | 0.30 (0.26) | 0.013 | 1.21 (0.71) | 0.025 |
| Controls (N = 10) | 0.00 (0.00) | 0.00 (0.00) | 0.01 (0.05) | 0.20 (0.63) | |||||
| Total (N = 20) | 0.86 (1.34) | 1.56 (2.29) | 0.16 (0.23) | 0.70 (0.83) | |||||
| Post Dark | Patients (N = 10) | 1.55b (1.47) | 0.089 | 2.48 (3.01) | 0.003 | 0.21 (0.23) | 0.111 | 1.10 (1.07) | 0.247 |
| Controls (N = 10) | 0.00 (0.00) | 0.10 (0.32) | 0.04 (0.07) | 0.50 (0.85) | |||||
| Total (N = 20) | 0.78 (1.28) | 1.29 (2.41) | 0.12 (0.18) | 0.80 (0.99) | |||||
aGroup comparisons using Quade analysis of covariance (adjusted for multiple comparisons using false discovery rate (FDR))
bSignificant post-hoc comparisons between study phases (FDR-corr.)