Table 2.
Comparative clinico-pathological characteristics and risk group assignments in the study cohort between clinical based characterisation (DRE + systematic sampling only) versus MRI based characterisation (MRI staging and combined MRI targeted and systematic sampling) in MRI-prebiopsy cohort. *no T4 cases in this cohort, see methods for how stage was assigned for clinical and MRI assignment. European Association of Urology (EAU), American Urological Association, Cambridge Prognostic Group (CPG)
Clinical stage and systematic biopsies | MRI stage and target systematic biopsies | Comparison | |||
---|---|---|---|---|---|
n | Percentage (%) | n | Percentage (%) | (%) | |
Stage * | |||||
T1-T2 | 263 | 71.1 | 234 | 63.2 | -7.8 |
T3 | 107 | 28.9 | 136 | 36.8 | 7.8 |
Grade Group | |||||
1 | 101 | 27.3 | 96 | 25.9 | -1.4 |
2 | 123 | 33.2 | 133 | 35.9 | 2.7 |
3 | 60 | 16.2 | 63 | 17.0 | 0.8 |
4 | 13 | 3.5 | 17 | 4.6 | 1.1 |
5 | 57 | 15.4 | 61 | 16.5 | 1.1 |
Benign | 16 | 4.3 | - | - | -4.3 |
EAU (Cancers only) | (n = 354) | (n = 370) | |||
Low risk | 67 | 18.9 | 66 | 17.8 | -1.1 |
Intermediate risk | 155 | 43.8 | 143 | 38.7 | -5.1 |
High | 132 | 37.3 | 161 | 43.5 | 6.2 |
AUA (Cancers only) | |||||
Low risk | 67 | 18.9 | 66 | 17.8 | -1.1 |
Favourable intermediate risk | 86 | 24.3 | 78 | 21.1 | -3.2 |
Unfavourable intermediate risk | 69 | 19.5 | 65 | 17.6 | -1.9 |
High risk | 132 | 37.3 | 161 | 43.5 | 6.2 |
CPG (Cancers only) | |||||
1 | 67 | 18.9 | 66 | 17.8 | -1.1 |
2 | 86 | 24.3 | 78 | 21.1 | -3.2 |
3 | 69 | 19.5 | 65 | 17.6 | -1.9 |
4 | 64 | 18.1 | 83 | 22.4 | 4.3 |
5 | 68 | 19.2 | 78 | 21.1 | 1.9 |