Skip to main content
. 2022 Aug 11;14:86. doi: 10.1186/s13073-022-01090-2

Table 1.

Tumors selected for DNA sequencing strategies, based on clinical responsea

WESb (n= 51) Docetaxel responder Docetaxel non-responder Docetaxel not evaluable
CR PR SD PD
Epirubicin responder CR 2 (1)
PR 2 (1) 6 (3) 13 (4) 2 (0)
Epirubicin non-responder SD 8 (1) 15 (0)
PD 2 (1) 1 (0)
Ampliconc (n= 45) Docetaxel responder Docetaxel non-responder Docetaxel not evaluable
CR PR SD PD
Epirubicin responder CR 1 (0)
PR 4 (0) 2 (0) 9 (1) 2 (1)
Epirubicin non-responder SD 1 (0) 3 (1) 21 (0) 1 (0) 1 (0)
PD

Numbers in paratheses indicate patients with pCR at surgery

aTumors selected as response outliers (response per RECIST) and with tumor tissue available for DNA extraction (n = 96/109)

bWES whole exome sequencing

cAmplicon: amplicon-based sequencing of 6-gene panel