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. 2022 Aug 11;19:18. doi: 10.1186/s11556-022-00297-x

Table 2.

GRADE quality of evidence table for estimates using muscle power, activity-based tests, and physical activity level in daily life in older adults

Certainty assessment Number of patients Effect Certainty Importance
Number of studies Study design Risk of bias Inconsist-ency Indirectness Imprecision Other considerations Power training Strength training Relative (95% CI) Absolute (95% CI)
Muscle power (upper extremity)
6 randomized trials serious a not serious b,c,d not serious e,f,g not serious h all plausible residual confounding would suggest spurious effect, while no effect was observed 90 90 SMD 0.99 SD higher(0.34 higher to 1.65 higher) ⨁⨁⨁⨁ HIGH IMPORTANT
Muscle power (lower extremity)
10 randomized trials serious a very serious b,i,j not serious e,f,g not serious h publication bias strongly suspected very strong association all plausible residual confounding would suggest spurious effect, while no effect was observed 203 204 SMD 1.00 SD higher(0.40 higher to 1.60 higher) ⨁⨁⨁◯ MODERATE IMPORTANT
Generic tests
11 randomized trials serious a not serious b,c,j not serious e,f,g not serious h strong association all plausible residual confounding would suggest spurious effect, while no effect was observed 424 429 SMD 0.43 SD higher(0.23 higher to 0.62 higher) ⨁⨁⨁⨁ HIGH CRITICAL
Tests with emphasis on movement speed
9 randomized trials serious a not serious b,d,i not serious e,f,g not serious h strong association all plausible residual confounding would suggest spurious effect, while no effect was observed 202 215 SMD 0.36 SD higher(0.04 higher to 0.6 higher) ⨁⨁⨁⨁ HIGH IMPORTANT

Legend: a Studies that carried large weight for the overall effect estimated as high risk of bias due to lack of construct validity for the intervention and the test and a lack of allocation concealment b (Unexplained) Inconsistency, with point estimates different. c Substantially overlap in confidence interval d I2 is less than 60% e No differences in population, f Substantial differences in outcome measures g Substantial differences in interventions h The 95% CI showed a moderate to good effect of powertraining in all articles i Confidence intervals do not overlap. j I2 is more than 60%