Table 2.
GRADE quality of evidence table for estimates using muscle power, activity-based tests, and physical activity level in daily life in older adults
| Certainty assessment | Number of patients | Effect | Certainty | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of studies | Study design | Risk of bias | Inconsist-ency | Indirectness | Imprecision | Other considerations | Power training | Strength training | Relative (95% CI) | Absolute (95% CI) | ||
| Muscle power (upper extremity) | ||||||||||||
| 6 | randomized trials | serious a | not serious b,c,d | not serious e,f,g | not serious h | all plausible residual confounding would suggest spurious effect, while no effect was observed | 90 | 90 | – | SMD 0.99 SD higher(0.34 higher to 1.65 higher) | ⨁⨁⨁⨁ HIGH | IMPORTANT | 
| Muscle power (lower extremity) | ||||||||||||
| 10 | randomized trials | serious a | very serious b,i,j | not serious e,f,g | not serious h | publication bias strongly suspected very strong association all plausible residual confounding would suggest spurious effect, while no effect was observed | 203 | 204 | – | SMD 1.00 SD higher(0.40 higher to 1.60 higher) | ⨁⨁⨁◯ MODERATE | IMPORTANT | 
| Generic tests | ||||||||||||
| 11 | randomized trials | serious a | not serious b,c,j | not serious e,f,g | not serious h | strong association all plausible residual confounding would suggest spurious effect, while no effect was observed | 424 | 429 | – | SMD 0.43 SD higher(0.23 higher to 0.62 higher) | ⨁⨁⨁⨁ HIGH | CRITICAL | 
| Tests with emphasis on movement speed | ||||||||||||
| 9 | randomized trials | serious a | not serious b,d,i | not serious e,f,g | not serious h | strong association all plausible residual confounding would suggest spurious effect, while no effect was observed | 202 | 215 | – | SMD 0.36 SD higher(0.04 higher to 0.6 higher) | ⨁⨁⨁⨁ HIGH | IMPORTANT | 
Legend: a Studies that carried large weight for the overall effect estimated as high risk of bias due to lack of construct validity for the intervention and the test and a lack of allocation concealment b (Unexplained) Inconsistency, with point estimates different. c Substantially overlap in confidence interval d I2 is less than 60% e No differences in population, f Substantial differences in outcome measures g Substantial differences in interventions h The 95% CI showed a moderate to good effect of powertraining in all articles i Confidence intervals do not overlap. j I2 is more than 60%