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. 2022 Aug 11;8(8):e10148. doi: 10.1016/j.heliyon.2022.e10148

Table 2.

Associations between musculoskeletal symptoms and demographic characteristics and COVID-19 course in participants.

Symptom Gender
Presence of underlying disease
Hospitalization
ICU admission
Occupation
Male Female P-value Yes No P-value Yes No P-value Yes No P-value Unemployed HCW Other P-value
Fatigue No 3 (4.2%) 18 (10.8%) 0.132 3 (7.3%) 18 (9.1%) 0.007 2 (8.7%) 19 (8.8%) 0.169 1 (10.0%) 20 (8.7%) 0.984 7 (9.9%) 1 (2.2%) 13 (10.7%) 0.055
0–4 weeks 41 (56.9%) 74 (44.3%) 17 (41.5%) 98 (49.5%) 8 (34.8%) 107 (49.5%) 5 (50.0%) 110 (48.0%) 27 (38.0%) 21 (45.7%) 67 (54.9%)
4–12 weeks 14 (19.4%) 46 (27.5%) 6 (14.6%) 54 (27.3%) 5 (21.7%) 55 (25.5%) 2 (20.0%) 58 (25.3%) 20 (28.2%) 17 (37.0%) 23 (18.9%)
>12 weeks 14 (19.4%) 29 (17.4%) 15 (36.6%) 28 (14.1%) 8 (31.8%) 35 (16.2%) 2 (20.0%) 41 (17.9%) 17 (23.9%) 7 (15.2%) 19 (15.6%)
Headache No 30 (41.7%) 60 (35.9%) 0.461 8 (19.5%) 82 (41.4%) 0.059 9 (39.1%) 81 (37.5%) 0.459 3 (30.0%) 87 (38.0%) 0.339 16 (22.5%) 22 (47.8%) 52 (42.6%) 0.059
0–4 weeks 29 (40.3%) 79 (47.3%) 23 (56.1%) 85 (42.9%) 8 (34.8%) 100 (46.3%) 4 (40.0%) 104 (45.4%) 42 (59.2%) 16 (34.8%) 50 (41.0%)
4–12 weeks 10 (13.9%) 16 (9.6%) 7 (17.1%) 19 (9.6%) 3 (13.0%) 23 (10.6%) 1 (10.0%) 25 (10.9%) 8 (11.3%) 4 (8.7%) 14 (11.5%)
>12 weeks 3 (4.2%) 12 (7.2%) 3 (7.3%) 12 (6.1%) 3 (13.0%) 12 (13.0%) 2 (20.0%) 13 (5.7%) 5 (7.0%) 4 (8.7%) 6 (4.9%)
Arthralgia No 26 (36.1%) 66 (39.5%) 0.163 16 (39.0%) 76 (38.4%) 0.186 9 (39.1%) 83 (38.4%) 0.009 5 (50.0%) 87 (38.0%) 0.491 25 (35.2%) 18 (39.1%) 49 (40.2%) 0.106
0–4 weeks 37 (51.4%) 64 (38.3%) 13 (31.7%) 88 (44.4%) 5 (21.7%) 96 (44.4%) 2 (20.0%) 99 (43.2%) 26 (36.6%) 20 (43.5%) 55 (45.1%)
4–12 weeks 5 (6.9%) 15 (9.0%) 4 (9.8%) 16 (8.1%) 2 (8.7%) 18 (8.3%) 1 (10.0%) 19 (8.3%) 6 (8.5%) 6 (13.0%) 8 (6.6%)
>12 weeks 4 (5.6%) 22 (13.2%) 8 (19.5%) 18 (9.1%) 2 (30.4%) 19 (8.8%) 2 (20.0%) 24 (10.5%) 14 (19.7%) 2 (4.3%) 10 (8.2%)
Myalgia No 13 (18.1%) 34 (20.4%) 0.326 6 (14.6%) 41 (20.7%) 0.007 6 (26.1%) 41 (19.0%) 0.066 3 (30.0%) 44 (19.2%) 0.052 11 (15.5%) 6 (13.0%) 30 (24.6%) 0.052
0–4 weeks 48 (66.7%) 92 (55.1%) 21 (51.2%) 119 (60.1%) 9 (39.1%) 131 (60.6%) 2 (20.0%) 138 (60.3%) 38 (53.5%) 29 (63.0%) 73 (59.8%)
4–12 weeks 6 (8.3%) 19 (11.4%) 3 (7.3%) 22 (11.1%) 2 (8.7%) 23 (10.6%) 3 (30.0%) 22 (9.6%) 9 (12.7%) 8 (17.4%) 8 (6.6%)
>12 weeks 5 (6.9%) 22 (13.2%) 11 (26.8%) 16 (8.1%) 6 (26.1%) 21 (9.7%) 2 (20.0%) 25 (10.9%) 9 (12.7%) 3 (6.5%) 11 (9.0%)
Neck pain No 52 (72.2%) 113 (67.7%) 0.591 22 (53.7%) 143 (72.2%) 0.009 18 (78.3%) 147 (68.1%) 0.270 8 (80.0%) 157 (68.6%) 0.755 46 (64.8%) 30 (35.2%) 89 (73.0%) 0.214
0–4 weeks 14 (19.4%) 30 (18.0%) 8 (19.5%) 36 (18.2%) 2 (8.7%) 42 (19.4%) 1 (10.0%) 43 (18.8%) 14 (19.7%) 8 (17.4%) 22 (18.0%)
4–12 weeks 3 (4.2%) 9 (5.4%) 3 (7.3%) 9 (4.5%) 0 (0.0%) 12 (5.6%) 0 (0.0%) 12 (5.2%) 2 (2.8%) 5 (10.9%) 5 (4.1%)
>12 weeks 3 (4.2%) 15 (9.0%) 8 (19.5%) 10 (5.1%) 3 (13.0%) 15 (6.9%) 1 (10.0%) 17 (7.4%) 9 (12.7%) 3 (6.5%) 6 (4.9%)
Back pain No 43 (59.7%) 91 (54.5%) 0.704 19 (46.3%) 115 (58.1%) 0.319 14 (60.9%) 120 (55.6%) 0.769 9 (90.0%) 125 (54.6%) 0.126 38 (53.5%) 26 (56.5%) 70 (57.4%) 0.119
0–4 weeks 19 (26.4%) 43 (25.7%) 11 (26.8%) 51 (25.8%) 4 (17.4%) 58 (26.9%) 0 (0.0%) 62 (27.1%) 20 (28.2%) 8 (17.4%) 34 (27.9%)
4–12 weeks 6 (8.3%) 17 (10.2%) 5 (12.2%) 18 (9.1%) 3 (13.0%) 20 (9.3%) 1 (10.0%) 22 (9.6%) 4 (5.6%) 9 (19.6%) 10 (8.2%)
>12 weeks 4 (5.6%) 16 (9.6%) 6 (14.6%) 14 (7.1%) 2 (8.7%) 18 (8.3%) 0 (0.0%) 20 (8.7%) 9 (12.7%) 3 (6.5%) 8 (6.6%)
Low Back pain No 37 (51.4%) 82 (49.1%) 0.257 16 (39.0%) 103 (52.0%) 0.094 10 (43.5%) 109 (50.5%) 0.262 4 (40.0%) 115 (50.2%) 0.020 28 (39.4%) 26 (56.5%) 65 (53.3%) 0.235
0–4 weeks 27 (37.5%) 53 (31.7%) 14 (34.0%) 66 (33.3%) 6 (26.1%) 74 (34.3%) 1 (10.0%) 79 (34.5%) 28 (39.4%) 12 (26.1%) 40 (32.8%)
4–12 weeks 6 (8.3%) 15 (9.0%) 4 (9.8%) 17 (8.6%) 3 (13.0%) 18 (8.3%) 2 (20.0%) 19 (8.3%) 6 (8.5%) 6 (13.0%) 9 (7.4%)
>12 weeks 2 (2.8%) 17 (10.2%) 7 (17.1%) 12 (6.1%) 4 (17.4%) 15 (6.9%) 3 (30.0%) 16 (7.0%) 9 (12.7%) 2 (4.3%) 8 (6.6%)
Hip pain No 55 (76.4%) 130 (77.8%) 0.599 29 (70.7%) 156 (78.8%) 0.434 15 (65.2%) 170 (78.7%) 0.001 9 (90.0%) 176 (76.9%) 0.464 47 (66.2%) 38 (82.6%) 100 (82.2%) 0.088
0–4 weeks 13 (18.1%) 22 (13.2%) 7 (17.1%) 28 (14.1%) 3 (13.0%) 32 (14.8%) 0 (0.0%) 35 (15.3%) 13 (18.3%) 6 (13.0%) 16 (13.1%)
4–12 weeks 2 (2.8%) 5 (3.0%) 1 (2.4%) 6 (3.0%) 0 (0.0%) 7 (3.2%) 0 (0.0%) 7 (3.1%) 3 (4.2%) 1 (2.2%) 3 (2.5%)
>12 weeks 2 (2.8%) 10 (6.0%) 4 (9.8%) 8 (4.0%) 5 (21.7%) 7 (3.2%) 1 (10.0%) 11 (4.8%) 8 (11.3%) 1 (2.2%) 3 (2.5%)
Leg pain No 35 (48.6%) 63 (37.7%) 0.248 10 (24.4%) 88 (44.4%) 0.085 9 (39.1%) 89 (41.2%) 0.141 5 (50.0%) 93 (40.6%) 0.296 24 (33.8%) 17 (37.0%) 57 (46.7%) 0.173
0–4 weeks 25 (34.7%) 62 (37.1%) 17 (41.5%) 70 (35.4%) 5 (21.7%) 82 (38.0%) 1 (10.0%) 86 (37.6%) 26 (36.6%) 19 (41.3%) 4 2 (34.4%)
4–12 weeks 7 (9.7%) 17 (10.2%) 6 (14.6%) 18 (9.1%) 3 (13.0%) 21 (9.7%) 2 (20.0%) 22 (9.6%) 6 (8.5%) 6 (13.0%) 12 (9.8%)
>12 weeks 5 (6.9%) 25 (15.0%) 8 (19.5%) 22 (11.1%) 6 (26.1%) 24 (11.1%) 2 (20.0%) 28 (12.2%) 15 (21.1%) 4 (8.7%) 11 (9.0%)
Chest pain No 38 (52.8%) 105 (62.9%) 0.134 19 (46.3%) 124 (62.6%) 0.176 11 (47.8%) 132 (61.1%) 0.058 6 (60.0%) 137 (59.8%) 0.279 36 (50.7%) 30 (65.2%) 77 (63.1%) 0.343
0–4 weeks 21 (29.2%) 45 (26.9%) 17 (41.5%) 49 (24.7%) 5 (21.7%) 61 (28.2%) 1 (10.0%) 65 (28.4%) 24 (33.8%) 11 (23.9%) 31 (25.4%)
4–12 weeks 6 (8.3%) 12 (7.2%) 3 (7.3%) 15 (7.6%) 4 (17.4%) 14 (6.5%) 2 (20.0%) 16 (7.0%) 8 (11.3%) 8 (8.7%) 6 (4.9%)
>12 weeks 7 (9.7%) 5 (3.0%) 2 (4.9%) 10 (5.1%) 3 (13.0%) 9 (4.2%) 1 (10.0%) 11 (4.8%) 3 (4.2%) 1 (2.2%) 8 (6.6%)
Bedridden due to fatigue No 41 (56.9%) 97 (58.1%) 0.070 20 (48.8%) 118 (59.6%) 0.102 3 (13.0%) 135 (62.5%) 0.001> 0 (0.0%) 138 (60.3%) 0.001> 36 (50.7%) 26 (56.5%) 76 (62.3%) 0.465
0–4 weeks 28 (38.9%) 46 (27.5%) 13 (31.7%) 61 (30.8%) 13 (56.5%) 61 (28.2%) 6 (60.0%) 68 (29.7%) 23 (32.4%) 16 (34.8%) 35 (28.7%)
4–12 weeks 2 (2.8%) 10 (6.0%) 2 (4.9%) 10 (5.1%) 3 (13.0%) 9 (4.2%) 1 (10.0%) 11 (4.8%) 4 (5.6%) 2 (4.3%) 6 (4.9%)
>12 weeks 1 (1.4%) 14 (8.4%) 6 (14.6%) 9 (4.5%) 4 (17.4%) 11 (5.1%) 3 (30.0%) 12 (5.2%) 8 (11.3%) 2 (4.3%) 5 (4.1%)
Bedridden due to pain No 61 (84.7%) 114 (68.3%) 0.037 29 (70.7%) 146 (73.7%) 0.097 13 (56.5%) 162 (75.0%) 0.024 5 (50.0%) 170 (74.2%) 0.003 41 (57.7%) 36 (78.3%) 98 (80.3%) 0.018
0–4 weeks 10 (13.9%) 37 (22.2%) 7 (17.1%) 40 (20.2%) 5 (21.7%) 42 (19.4%) 2 (20.0%) 45 (19.7%) 20 (28.2%) 8 (17.4%) 19 (15.6%)
4–12 weeks 0 (0.0%) 5 (3.0%) 0 (0.0%) 5 (2.5%) 1 (4.3%) 4 (1.9%) 0 (0.0%) 5 (2.2%) 2 (2.8%) 1 (2.2%) 2 (1.6%)
>12 weeks 1 (1.4%) 11 (6.6%) 5 (12.2%) 7 (3.5%) 4 (17.4%) 8 (3.7%) 3 (30.0%) 9 (3.9%) 8 (11.3%) 1 (2.2%) 3 (2.5%)
Shortness of breath in rest No 43 (59.7%) 120 (71.9%) 0.126 15 (36.6%) 135 (68.2%) 0.260 10 (43.5%) 153 (70.8%) 0.003 2 (20.0%) 158 (69.0%) 0.352 33 (46.5%) 31 (67.4%) 61 (50.0%) 0.106
0–4 weeks 24 (33.3%) 32 (19.2%) 12 (29.3%) 46 (23.2%) 10 (43.5%) 46 (21.3%) 4 (40.0%) 52 (22.7%) 18 (25.4%) 14 (30.4%) 32 (26.2%)
4–12 weeks 3 (4.2%) 10 (6.0%) 6 (14.6%) 10 (5.1%) 1 (4.3%) 12 (5.6%) 2 (20.0%) 13 (5.7%) 10 (14.1%) 1 (2.2%) 15 (12.3%)
>12 weeks 2 (2.8%) 5 (3.0%) 8 (19.5%) 7 (3.5%) 2 (8.7%) 5 (2.3%) 2 (20.0%) 6 (2.6%) 10 (14.1%) 0 (0.0%) 14 (11.5%)
Shortness of breath in activity No 31 (43.1%) 83 (49.7%) 0.754 28 (68.3%) 99 (50.0%) 0.617 4 (17.4%) 110 (50.9%) 0.022 5 (50.0%) 112 (48.9%) 0.253 41 (57.7%) 20 (43.5%) 91 (74.6%) 0.883
0–4 weeks 21 (29.2%) 42 (25.1%) 10 (24.4%) 51 (25.8%) 7 (30.4%) 56 (25.9%) 4 (40.0%) 59 (25.8%) 21 (29.6%) 13 (28.3%) 21 (17.2%)
4–12 weeks 10 (13.9%) 24 (14.4%) 3 (7.3%) 28 (14.1%) 5 (21.7%) 29 (13.4%) 0 (0.0%) 32 (14.0%) 5 (7.0%) 9 (19.6%) 7 (5.7%)
>12 weeks 10 (13.9%) 18 (10.8%) 0 (0.0%) 20 (10.1%) 2 (8.7%) 21 (9.7%) 1 (10.0%) 26 (11.4%) 4 (5.6%) 4 (8.7%) 3 (2.5%)

Values are reported as number (%). Statistically significant values are bolded.