Table 3.
Low performance group (n=9) | Adjusted OR (95% CI) | High performance group (n=9) | Adjusted OR (95% CI) | |||||||
Baseline | End of course | Baseline | End of course | |||||||
All cases (n=30) | ||||||||||
Tumour category* | 62% | (158/255) | 77% | (202/264) | 2.60 (1.68 to 4.02) | 75% | (202/269) | 76% | (204/269) | 1.05 (0.67 to 1.63) |
Tumour stage, early vs advanced† | 86% | (220/255) | 89% | (235/263) | 1.50 (0.82 to 2.73) | 93% | (247/266) | 94% | (252/268) | 1.27 (0.61 to 2.63) |
Tumour height category | 74% | (192/260) | 81% | (214/265) | 1.75 (1.08 to 2.86) | 83% | (223/268) | 84% | (226/269) | 1.10 (0.63 to 1.93) |
Tumour location | 1.76 | ±0.30 | 1.33 | ±0.39 | 0.42 (0.19 to 0.64) | 1.29 | ±0.60 | 0.94 | ±0.39 | 0.35 (0.13 to 0.57) |
Lymph node status | 86% | (221/256) | 89% | (235/263) | 1.40 (0.80 to 2.43) | 86% | (231/268) | 81% | (218/268) | 0.63 (0.37 to 1.07) |
EMVI status | 79% | (182/229) | 79% | (199/251) | 0.98 (0.58 to 1.65) | 78% | (198/254) | 87% | (232/267) | 2.36 (1.38 to 4.04) |
Cases with T3 or T4 tumours (n=19) | ||||||||||
Tumour-free MRF, 5 mm level | 49% | (33/68) | 76% | (50/66) | 10.80 (3.75 to 31.17) | 88% | (58/66) | 87% | (59/68) | 0.83 (0.23 to 3.00) |
Tumour-free MRF, 1 mm level | 68% | (52/77) | 87% | (65/75) | 6.89 (2.56 to 18.52) | 91% | (68/75) | 89% | (68/76) | 0.84 (0.24 to 2.93) |
Data are percentages (number/total) and OR for agreeing with the reference standard (95% CI), except for tumour location, which is the difference between the clock face centre of the tumour derived from the participants’ registrations compared with the ones derived from the reference standard, expressed as means (hours), SD and difference of means from baseline to end of course (95% CI).
*Tumour category: T1, T2, T3, T4.
†Early tumours: T1, T2, T3a–b; advanced tumours: T3c–d, T4a–b.
EMVI, extramural vascular invasion; MRF, mesorectal fascia.