Table 4.
Univariate and multivariate analysis of predictors of mortality, and relationship of mortality with the timing of drainage for each predictor
| Predictors (n = 1305) |
Univariate analysis
|
Multivariate analysis
|
Mortality to the timing of drainage
|
||||||||||
|
OR (95%CI)
|
P
value
|
OR (95%CI)
|
P
value
|
< 12 h
|
> 12 h or absence
|
P
value
|
< 24 h
|
> 24 h or absence
|
P
value
|
< 48 h
|
> 48 h or absence
|
P
value
|
|
| Neurological dysfunction | 8.377 (4.384-16.007) | < 0.001 | 5.32 (2.373-11.931) | < 0.001 | 0/22 | 18/104 | 0.041 | 3/42 | 15/84 | 0.175 | 5/51 | 13/75 | 0.304 |
| Respiratory dysfunction | 2.886 (1.491-5.497) | 0.003 | 2.541 (1.189-5.43) | 0.016 | 1/44 | 14/183 | 0.314 | 4/91 | 11/136 | 0.414 | 6/117 | 9/110 | 0.428 |
| Renal dysfunction | 11.043 (5.402-22.573) | < 0.001 | 6.356 (2.623-15.397) | < 0.001 | 1/15 | 12/49 | 0.269 | 1/28 | 12/36 | 0.004 | 1/31 | 12/33 | 0.001 |
| Cardiovascular dysfunction | 11.569 (5.078-26.357) | < 0.001 | 4.021 (1.361-11.88) | 0.012 | 0/7 | 9/32 | 0.169 | 2/16 | 7/23 | 0.262 | 2/18 | 7/21 | 0.139 |
| Hematological dysfunction | 2.611 (1.253-5.441) | 0.02 | N/A | 2/37 | 8/104 | 1 | 3/61 | 7/88 | 0.527 | 3/74 | 7/75 | 0.327 | |
| Hepatic dysfunction | 5.263 (2.484-11.152) | < 0.001 | N/A | 0/15 | 10/68 | 0.196 | 1/30 | 9/53 | 0.086 | 1/39 | 9/44 | 0.016 | |
| Age (≥ 75 yr) | 1.432 (0.765-2.680) | 0.261 | N/A | 2/88 | 21/531 | 0.759 | 4/196 | 19/423 | 0.172 | 7/267 | 16/352 | 0.284 | |
| Temperature (≥ 39 ℃) | 0.390 (0.093-1.631) | 0.197 | N/A | 0/43 | 2/106 | 1 | 1/75 | 1/74 | 1 | 1/85 | 1/64 | 1 | |
| WBC (> 12000/mm3, < 4000/mm3) | 1.962 (1.043-3.688) | 0.036 | N/A | 1/107 | 23/445 | 0.063 | 4/207 | 20/342 | 0.031 | 6/278 | 18/275 | 0.012 | |
| T-Bil (≥ 5 mg/dL) | 1.711 (0.865-3.385) | 0.123 | N/A | 3/143 | 26/626 | 0.333 | 5/292 | 24/477 | 0.019 | 8/407 | 21/362 | 0.007 | |
| Albumin (< STD*0.7) | 10.715 (5.147-22.303) | < 0.001 | 5.655 (2.398-13.335) | < 0.001 | 0/8 | 12/51 | 0.188 | 0/15 | 12/44 | 0.026 | 1/24 | 11/35 | 0.018 |
| Lactate (≥ 2 mmol/L) | 1.450 (0.766-2.747) | 0.254 | N/A | 0/105 | 16/298 | 0.016 | 2/186 | 14/217 | 0.008 | 4/227 | 12/176 | 0.018 | |
| Malignant obstruction | 5.495 (2.924-10.325) | < 0.001 | 7.522 (3.504-16.149) | < 0.001 | 1/26 | 21/216 | 0.483 | 2/59 | 20/183 | 0.116 | 3/101 | 19/141 | 0.006 |
| CCI (> 3) | 4.080 (2.153-7.7340) | < 0.001 | N/A | 2/57 | 23/318 | 0.397 | 4/127 | 21/248 | 0.052 | 6/177 | 19/198 | 0.021 | |
WBC: White blood cell count; T-Bil: Total bilirubin; STD: Lower limit of normal value; CCI: Charlton Comorbidity Index; OR: Odds ratio; CI: Confidence interval; N/A: Not applicable.