Table 3.

Clinical and radiographic findings of COVID-19 pneumonia, immune-checkpoint pneumonitis, and radiation pneumonitis.

COVID-19 Pneumonia	Immune-Checkpoint Inhibitor Pneumonitis	Radiation Therapy Induced Pneumonitis
Cough, fever, dyspnea	Cough, fever, dyspnea	Cough, fever, dyspnea
Bilateral involvement	Bilateral involvement	Unilateral, near treatment site
Ground glass opacities with reticular pattern, patchy consolidations, fibrotic and subpleural lines	Ground glass opacities, patchy peripheral consolidations, centrilobular nodules, interstitial and interseptal lobular thickening, volume loss, and traction bronchiectasis	Ground glass opacities, volume loss, linear fibrosis, consolidation, and traction bronchiectasis
High D-dimers, CRP, IL-6 and sIL-2R, and lymphopenia	High CRP, erythrocyte sedimentation, neutrophils, and lymphocytes	High CRP, erythrocyte sedimentation, ferritin and D-dimer, and lymphopenia
Can lead to ARDS	Can progress to ARDS	Can progress to ARDS