Table 6.
Reference | Type of Tissue | MMRd (n) | MMRd (%) | PDL-1 |
---|---|---|---|---|
Jones 2020 [161] | Not described | 203 | 33 | PDL-1 was more frequent in MMRd tumors |
Bregar 2017 [88] | FFPE | 13 | 33 | PDL-1 was present in 62% of MMRd tumors and high-grade tumors vs. 46% in MMRp tumors |
Sloan 2017 [95] | FFPE | 38 | 56.7 | 100% MMRd tumors demonstrated PDL-1 expression in peritumoral immune compartment |
Rowe 2020 [136] | FFPE | 43 | 69.4 | 60.4% MMRd tumors showed positive tumoral PDL-1 vs. 5.3% MMRp |
FFPE: formalin-fixed paraffin-embedded, MMRd: mismatch repair-deficient.