Table 3.

Reports on prognostic factors in patients with ER for SESCC.

Authors, Year	Study Population	No. of Subjects	Study Design	Prognostic Factors
Nakajo et al., 2019 [50]	75 years	360	Multicenter, retrospective	CCI ≥ 2
Ogata et al., 2021 [49]	All	407	Single-center, retrospective	Early mortality: ECOG-PS ≥ 2, CCI ≥ 2; Late mortality: ECOG-PS ≥ 2, CCI ≥ 2, age ≥ 80 years
Suzuki et al., 2021 [51]	pT1a-EP/LPM/MM or pT1b-SM1	286	Single-center, retrospective	PNI < 45, CCI ≥ 3
Iwai et al., 2021 [52]	All	659	Multicenter, retrospective	pT1a-MM/pT1b-SM1, pT1b-SM2, CCI ≥ 3, PNI ≤ 47.75
Hirano et al., 2022 [53]	PS-matched cohort	138	Single-center, retrospective	ASA-PS = 3
Shimada et al., 2022 [54]	pT1a-MM/pT1b-SM	593	Multicenter, retrospective	Male, CCI ≥ 3, ≥ 75 years, PNI < 45, pathological intermediate-/high-risk 1

¹ According to the pathological risk classification after non-curative ER for SESCC [28]. ASA-PS, American Society of Anesthesiologists physical status; CCI, Charlson comorbidity index; ECOG-PS, Eastern Cooperative Oncology Group performance status; ER, endoscopic resection; PNI, prognostic nutrition index; PS, propensity score; pT1a-EP/LPM, tumor invasion confined to the epithelium or lamina propria mucosa; pT1a-MM, tumor invasion confined to the muscularis mucosa; pT1b-SM1, tumor invasion confined to the submucosa ≤200 µm; pT1b-SM2, tumor invasion into the submucosa >200 µm; SESCC, superficial esophageal squamous cell carcinoma.