Table 3.
Top 5 clusters with their representative enriched terms (one per cluster) from pathway enrichment analysis. “Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10(P)” is the p-value in log base 10. “Log10(q)” is the multi-test adjusted p-value in log base 10.
| GO | Description | Count | % | Log10(p) | Log10(q) | Genes |
|---|---|---|---|---|---|---|
| R-HSA-156711 | Polo-like-kinase-mediated events | 5 | 20.83 | −7.07 | −2.84 | CCNB1, CENPF, FOXM1, PLK1, CCNB2, IGF1, TOP2A, TPX2 |
| R-HSA-69273 | Cyclin-A/B1/B2-associated events during G2/M transition | 6 | 25 | −6.85 | −2.84 |
CCNA2, CCNB1, CDK1, FOXM1, PLK1, CCNB2, CENPF, PCNA, TOP2A, ANLN, IGF1, DTL, ECT2, TPX2, EDN3, KIF23, NUSAP1, MKI67, EZR |
| M5893 | HALLMARK MITOTIC SPINDLE | 12 | 50 | −6.12 | −2.42 |
CDK1, CENPF, ECT2, KIF11, PLK1, TOP2A, EZR, CCNB2, KIF23, TPX2, NUSAP1, ANLN, CCNA2, MKI67, CCNB1, CKAP2, ASPM |
| WP2361 | Gastric cancer network 1 | 4 | 16.67 | −3.96 | −0.94 | CENPF, ECT2, TOP2A, TPX2 |
| GO:0030866 | Cortical actin cytoskeleton organization | 3 | 12.5 | −3.14 | −0.4 | ECT2, EZR, ANLN, IGF1, CCT5 |