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. 2022 Jul 28;13:894277. doi: 10.3389/fimmu.2022.894277

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Copyright © 2022 Romero-Ibarguengoitia, González-Cantú, Pozzi, Levi, Mollura, Sarti, Sanz-Sánchez, Rivera-Salinas, Hernández-Ruíz, Armendariz-Vázquez, Del Rio-Parra, Barco-Flores, González-Facio, Azzolini, Barbieri, de Azevedo Dias, Henriques Guimarães Júnior, Bastos-Borges, Acciardi, Paez-Bo, Teixeira and Rescigno

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plot for the GLM Poisson model coefficients stratified by SARS-CoV-2 history. Women and young individuals developed more severe or systemic AEFI (AEs). There was no effect of Body Mass Index. In the naïve SARS-CoV-2 cohort, the vaccines Gam-COVID-Vac, Coronavac and ChAdOx1-S were related to fewer AEs after the second dose than BNT162b mRNA. However, for naïve SARS-CoV-2 patients who received Gam-COVID-Vac, higher antibody levels after the second dose were related to a greater number of AEs. In people previously exposed to SARS-CoV-2, those receiving Gam-COVID-Vac showed a greater number of AEs compared to BNT162b mRNA, while subjects receiving Coronavac showed significantly fewer events when compared to BNT162b mRNA.