Table 2.
Tumor characteristics, grade, SEER stage, and location in 10,833 patients with gastrointestinal stromal tumors from the Surveillance, Epidemiology, and End Results (SEER) database 2000–2018.
| Variable | Frequency Total = 10,833 (n, %) |
|
|---|---|---|
| Primary Site | Stomach | 6868 (63.4) |
| Small Intestine | 3283 (30.3) | |
| Rectum | 307 (2.8) | |
| Esophagus | 71 (0.7) | |
| Large intestine (any site) | 251 (2.3) | |
| Sigmoid colon | 61 (0.6) | |
| Cecum | 46 (0.4) | |
| Descending Colon | 36 (0.3) | |
| Ascending Colon | 36 (0.3) | |
| Large Intestine, NOS | 32 (0.3) | |
| Transverse Colon | 29 (0.3) | |
| Rectosigmoid Junction | 19 (0.2) | |
| Hepatic Flexure | 17 (0.2) | |
| Splenic Flexure | 4 (0.03) | |
| Appendix | 13 (0.1) | |
| Anus, anal canal, and anoderm | 11 (0.1) | |
| Stage * | Unknown | 1523 (14) |
| Known | 9310 (86) | |
| Localized | 6129 (65.8) | |
| Distant | 1774 (19.1) | |
| Regional | 1407 (15.1) | |
| Tumor Size | Unknown | 2833 (26.2) |
| Known tumor size | 8000 (73.8) | |
| <2cm | 592 (7.4) | |
| 2–5 cm | 2306 (28.8) | |
| 6–10 cm | 2865 (35.8) | |
| >10 cm | 2237 (28) | |
| Tumor Grade | Unknown | 6142 (56.7) |
| Known | 4691 (43.3) | |
| Well-differentiated | 1768 (37.7) | |
| Moderately differentiated | 1502 (32) | |
| Undifferentiated | 867 (18.5) | |
| Poorly differentiated | 554 (11.8) | |
* = The information related to the extent of the disease (EOD) was derived from the SEER summary-stage data collection system, which incorporates the EOD Primary Tumor, Regional Nodes, and Mets algorithm. EOD 0 = carcinoma in situ, 1 = organ-confined, 2 = regional extension, 3 = regional lymph nodes, 4 = direct extension, and regional lymph node involvement, 7 = distant extension, 8 = benign and borderline tumors, and 9 = extension and metastasis are unknown. (https://seer.cancer.gov/archive/manuals/2021/SPCSM_2021_MainDoc.pdf, accessed 13 July 2022).