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. 2022 Jul 28;14(15):3689. doi: 10.3390/cancers14153689

Table 4.

Reported treatment based on the grade, size, and stage of 10,833 patients with gastrointestinal stromal tumor from the Surveillance, Epidemiology, and End Results (SEER) database 2000–2018.

Tumor Size (n, %)
Treatment <2 cm 2–5 cm 6–10 cm >10 cm
Surgery 533 (90) 1796 (77.9) 1818 (63.4) 1283 (57.3)
Chemotherapy ± surgery 58 (9.8) 506 (21.9) 1042 (36.4) 947 (42.3)
Adjuvant radiation 1 (0.2) 4 (0.2) 4 (0.1) 6 (0.3)
Neoadjuvant radiation 0 0 1 (0.03) 1 (0.04)
Tumor Grade (n, %)
Treatment Well
differentiated
Moderately
differentiated
Undifferentiated/
anaplastic
Poorly
Differentiated
Surgery 1417 (80.1) 1062 (70.7) 523 (60.3) 338 (61)
Chemotherapy ± surgery 349 (19.7) 426 (28.4) 330 (38.1) 208 (37.5)
Adjuvant radiation 1 (0.05) 7 (0.5) 7 (0.7) 4 (0.7)
Neoadjuvant radiation 1 (0.05) 7 (0.5) 7 (0.7) 4 (0.7)
Tumor Stage (n, %)
Treatment Localized Distant Regional
Surgery 4895 (73.6) 1005 (44.9) 1245 (63.8)
Chemotherapy ± surgery 1735 (26.1) 1222 (54.6) 690 (35.4)
Adjuvant radiation 19 (0.3) 10 (0.4) 12 (0.6)
Neoadjuvant radiation 1 (0.01) 1 (0.04) 4 (0.2)