Table 9.
Univariate and multivariate analysis of factors affecting mortality among 10,833 patients with gastrointestinal stromal tumors from the Surveillance, Epidemiology, and End Results (SEER) database 2000–2018.
| Variables | Univariate | Multivariate Analysis | ||
|---|---|---|---|---|
| p-Value | Hazard Ratio (95% Confidence Interval) | p-Value | ||
| Age > 60 Years | <0.001 | 3.45 (1.81–6.61) | <0.001 | |
| Gender | Male | 0.767 | ||
| Female | ||||
| Location | Esophagus | 0.004 | 1.82 (1.25–2.72) | 0.004 |
| Stomach | 0.129 | |||
| Small Intestine | 0.847 | |||
| Cecum | 0.052 | |||
| Appendix | 0.316 | |||
| Ascending Colon | 0.003 | 2.53 (2.35–3.21) | 0.003 | |
| Hepatic Flexure | 0.651 | |||
| Transverse Colon | 0.542 | |||
| Splenic Flexure | 0.212 | |||
| Descending Colon | 0.231 | |||
| Sigmoid Colon | 0.004 | 1.74 (1.28–2.34) | 0.004 | |
| Large intestine, NOS | 0.855 | |||
| Rectosigmoid Junction | 0.658 | |||
| Rectum | 0.645 | |||
| Anus, Anal Region, Anoderm | 0.669 | |||
| Size | <2 cm in size | 0.997 | ||
| 2–5 cm in size | 0.757 | |||
| >5 cm in size | 0.01 | 7.30 (1.11–47.87) | 0.003 | |
| Stage | Localized | 0.733 | ||
| Regional | 0.512 | |||
| Distant | 0.003 | 3.17 (1.26–7.24) | 0.001 | |
| Grade | Well-Differentiated | 0.679 | ||
| Moderately Differentiated | 0.13 | |||
| Poorly Differentiated | 0.003 | 5.35 (2.92–12.1) | <0.001 | |
| Undifferentiated | 0.003 | 5.35 (2.92–12.1) | <0.001 | |