Table 5.
Gene | SNP ID | gender | relapse | History of febrile seizure | periodic Seizure | Time to remission | Drug responsiveness | drug level | Family history of epilepsy | Epilepsy classification | Seizure classification |
---|---|---|---|---|---|---|---|---|---|---|---|
SCN1A | rs3812718 | 0.060 | 0.054 | 0.375 | 0.268 | 0.588 | 0.820 | 0.382 | 0.645 | 0.458 | 0.976 |
rs2298771 | 0.398 | 0.118 | 0.781 | 0.268 | 0.632 | 0.914 | 0.987 | 0.552 | 0.220 | 0.685 | |
rs10167228 | 0.124 | 0.322 | 0.670 | 0.489 | 0.347 | 0.947 | 0.053 | 0.426 | 0.436 | 0.661 | |
rs6432858 | 0.430 | 0.104 | 0.797 | 0.281 | 0.585 | 0.882 | 0.975 | 0.609 | 0.216 | 0.695 | |
rs10194956 | 0.189 | 0.272 | 0.156 | 0.618 | 0.771 | 0.248 | 0.018 | 0.491 | 0.953 | 0.477 | |
rs2169312 | 0.084 | 0.156 | 0.006 | 0.660 | 0.383 | 0.098 | 0.310 | 0.067 | 0.669 | 0.859 | |
rs1461197 | 0.137 | 0.549 | 0.203 | 0.062 | 0.088 | 0.664 | 0.155 | 0.206 | 0.337 | 0.101 | |
rs13405797 | 0.105 | 0.257 | 0.023 | 0.734 | 0.772 | 0.068 | 0.289 | 0.035 | 0.635 | 0.731 | |
rs4667866 | 0.896 | 0.324 | 0.988 | 0.497 | 0.317 | 0.454 | 0.599 | 0.910 | 0.759 | 0.218 | |
rs1020853 | 0.098 | 0.523 | 0.667 | 0.197 | 0.704 | 0.347 | 0.718 | 0.431 | 0.185 | 0.980 | |
rs1381105 | 0.054 | 0.376 | 0.051 | 0.346 | 0.136 | 0.348 | 0.518 | 0.035 | 0.521 | 0.378 | |
rs2162600 | 0.088 | 0.436 | 0.026 | 0.720 | 0.501 | 0.116 | 0.308 | 0.065 | 0.656 | 0.841 | |
rs10182473 | 0.099 | 0.500 | 0.167 | 0.530 | 0.073 | 0.228 | 0.247 | 0.114 | 0.359 | 0.769 | |
rs16851381 | 0.896 | 0.324 | 0.988 | 0.497 | 0.317 | 0.454 | 0.599 | 0.910 | 0.759 | 0.218 | |
rs4667869 | 0.082 | 0.490 | 0.238 | 0.378 | 0.428 | 0.195 | 0.704 | 0.344 | 0.509 | 0.779 | |
rs10497275 | 0.896 | 0.324 | 0.988 | 0.497 | 0.317 | 0.454 | 0.599 | 0.910 | 0.759 | 0.218 | |
rs6432861 | 0.388 | 0.055 | 0.208 | 0.431 | 0.742 | 0.898 | 0.415 | 0.588 | 0.561 | 0.993 | |
rs7580482 | 0.173 | 0.587 | 0.484 | 0.905 | 0.445 | 0.970 | 0.053 | 0.466 | 0.430 | 0.693 | |
rs13383628 | 0.228 | 0.215 | 0.155 | 0.728 | 0.823 | 0.262 | 0.040 | 0.574 | 0.958 | 0.471 | |
rs6722462 | 0.256 | 0.585 | 0.191 | 0.068 | 0.075 | 0.807 | 0.147 | 0.466 | 0.325 | 0.096 | |
rs6432860 | 0.391 | 0.091 | 0.777 | 0.264 | 0.587 | 0.921 | 0.990 | 0.644 | 0.170 | 0.682 | |
rs994399 | 0.191 | 0.546 | 0.472 | 0.882 | 0.408 | 0.939 | 0.051 | 0.517 | 0.424 | 0.703 | |
rs1542484 | 0.382 | 0.062 | 0.591 | 0.268 | 0.713 | 0.671 | 0.628 | 0.586 | 0.457 | 0.974 | |
rs1461193 | 0.139 | 0.293 | 0.655 | 0.508 | 0.314 | 0.979 | 0.051 | 0.476 | 0.430 | 0.671 | |
rs11690959 | 0.212 | 0.197 | 0.148 | 0.654 | 0.781 | 0.284 | 0.039 | 0.541 | 0.948 | 0.482 | |
rs7601520 | 0.193 | 0.456 | 0.930 | 0.649 | 0.447 | 0.904 | 0.050 | 0.639 | 0.550 | 0.666 | |
SCN2A | rs12467383 | 0.096 | 0.253 | 0.876 | 0.716 | 0.980 | 0.069 | 0.167 | 0.922 | 0.298 | 0.317 |
rs1965757 | 0.022 | 0.690 | 0.072 | 0.733 | 0.347 | 0.334 | 0.670 | 0.762 | 0.708 | 0.090 | |
rs353139 | 0.099 | 0.104 | 0.040 | 0.814 | 0.787 | 0.047 | 0.395 | 0.368 | 0.680 | 0.419 | |
rs7581811 | 0.035 | 0.115 | 0.586 | 0.711 | 0.906 | 0.262 | 0.919 | 0.872 | 0.767 | 0.517 | |
rs2116658 | 0.642 | 0.542 | 0.500 | 0.542 | 0.939 | 0.553 | 0.690 | 0.267 | 0.502 | 0.165 | |
rs12993173 | 0.082 | 0.248 | 0.370 | 0.643 | 0.909 | 0.584 | 0.831 | 0.531 | 0.882 | 0.602 | |
rs4667485 | 0.167 | 0.875 | 0.609 | 0.011 | 0.815 | 1.00 | 0.695 | 0.319 | 0.555 | 0.994 | |
rs1469649 | 0.257 | 0.841 | 0.679 | 0.040 | 0.911 | 0.774 | 0.594 | 0.743 | 0.228 | 0.782 | |
rs1579865 | 0.407 | 0.559 | 0.492 | 0.769 | 0.989 | 0.300 | 0.452 | 0.097 | 0.547 | 0.131 | |
rs935403 | 0.197 | 0.666 | 0.131 | 0.337 | 0.461 | 0.271 | 0.946 | 0.897 | 0.853 | 0.014 | |
rs7592445 | 0.021 | 0.717 | 0.052 | 0.720 | 0.624 | 0.430 | 0.574 | 0.793 | 0.848 | 0.102 | |
rs2119067 | 0.540 | 0.367 | 0.050 | 0.753 | 0.712 | 0.349 | 0.515 | 0.023 | 0.062 | 0.975 | |
rs2119068 | 0.266 | 0.059 | 0.132 | 0.209 | 0.452 | 0.519 | 0.941 | 0.692 | 0.294 | 0.918 | |
rs10197716 | 0.489 | 0.656 | 0.226 | 0.055 | 0.928 | 0.986 | 0.536 | 0.070 | 0.070 | 0.422 | |
rs353112 | 0.851 | 0.980 | 0.271 | 0.006 | 0.279 | 0.354 | 0.203 | 0.769 | 0.851 | 0.209 | |
rs6740895 | 0.374 | 0.945 | 0.986 | 0.614 | 0.650 | 0.148 | 0.276 | 0.478 | 0.821 | 0.840 | |
rs3943809 | 0.044 | 0.426 | 0.828 | 0.716 | 0.984 | 0.067 | 0.325 | 0.898 | 0.297 | 0.320 | |
rs16850331 | 0.066 | 0.347 | 0.783 | 0.583 | 0.947 | 0.042 | 0.151 | 0.802 | 0.174 | 0.813 | |
rs12614399 | 0.049 | 0.452 | 0.485 | 0.580 | 0.980 | 0.034 | 0.181 | 0.641 | 0.170 | 0.844 | |
rs10182570 | 0.712 | 0.954 | 0.782 | 0.001 | 0.711 | 0.455 | 0.378 | 0.833 | 0.039 | 0.578 | |
rs1446579 | 0.427 | 0.518 | 0.268 | 0.310 | 0.334 | 0.260 | 0.808 | 0.757 | 0.525 | 0.371 | |
SCN3A | rs7598098 | 0.024 | 0.277 | 0.980 | 0.350 | 0.751 | 0.972 | 0.571 | 0.194 | 0.923 | 0.235 |
rs12615864 | 0.662 | 0.740 | 0.935 | 0.538 | 0.798 | 0.862 | 0.292 | 0.118 | 0.418 | 0.260 | |
rs16850186 | 0.636 | 0.382 | 0.489 | 0.716 | 0.847 | 0.535 | 0.706 | 0.848 | 0.165 | 0.154 | |
rs1439806 | 0.622 | 0.900 | 0.726 | 0.277 | 0.190 | 0.544 | 0.115 | 0.821 | 0.971 | 0.895 | |
rs7596422 | 0.090 | 0.567 | 0.088 | 0.602 | 0.564 | 0.169 | 0.011 | 0.474 | 0.651 | 0.753 | |
SCN2B | rs8192613 | 0.798 | 0.125 | 0.730 | 0.465 | 0.367 | 0.963 | 0.464 | 0.135 | 0.655 | 0.864 |
rs8192614 | 0.626 | 0.612 | 0.150 | 0.257 | 0.438 | 0.291 | 0.415 | 0.660 | 0.256 | 0.551 | |
SCN3B | rs3851100 | 0.387 | 0.427 | 0.148 | 0.578 | 0.603 | 0.997 | 0.474 | 0.289 | 0.232 | 0.312 |
rs1783901 | 0.246 | 0.754 | 0.999 | 0.114 | 0.489 | 0.173 | 0.929 | 0.578 | 0.141 | 0.073 | |
SCN8A | rs303777 | 0.918 | 0.645 | 0.479 | 0.225 | 0.245 | 0.786 | 0.692 | 0.764 | 0.746 | 0.961 |
rs11169883 | 0.393 | 0.806 | 0.989 | 0.623 | 0.111 | 0.781 | 0.019 | 0.105 | 0.249 | 0.058 | |
rs303778 | 0.381 | 0.906 | 0.316 | 0.019 | 0.434 | 0.572 | 0.705 | 0.556 | 0.178 | 0.329 |
Linear regression using Pearson's r test.
p value <.05 is significant.