Table 3.

Kinetic parameters of metabolite production from toddalolactone in glucuronide metabolism.

Kinetic parameters	RLMs	MLMs	HLMs	RAMs	PLMs
V max	55.89 ± 6.61	187.53 ± 27.77	50.16 ± 8.75	11.98 ± 2.19	34.12 ± 3.62
K m	79.11 ± 22.56	154.51 ± 42.46	66.33 ± 20.46	91.46 ± 28.22	93.28 ± 22.35
CLint	0.69	1.21	0.75	0.12	0.36

K_m, V_max, and CL_int are expressed in units of µM, pmol/min/mg protein, and µL/min/mg protein, respectively.