Table 2.

Characteristics of patients with SLE in the literature with HLH during pregnancy.

Agey	Gestationalage	Associated factors	Clinical presentation	Treatment	Mode of delivery	Maternal Fetal		Bone marrow	Reference
28	22	SLE	Fever, pancytopenia, elevated triglycerides, ferritin, LDH. developed preeclampsia	IVIg, IV methylprednisolone, oral prednisone	Cesarean at 30 wk for Prom	Health	Health	hemophagocytosis	Pérard et al. (32)
28	5	SLE	Headaches, fevers, fatigue, and arthralgias. low C3 and elevated liver enzymes, leukopenia and thrombocytopenia	hydroxychloroquine, aspirin, prednisone, azathioprine, methylprednisolone, etoposide and dexamethasone, IVIg	Spontaneous abortion	Death	Abortion	hemophagocytosis	Parrott et al. (33)
20	10	SLE	NA	Corticosteroids, Cyclosporin A	Spontaneous abortion	Health	Abortion	NA	Song et al. (34)
23	12	SLE	Fever, elevated liver enzymes, triglycerides, CD25, ferritin, triglycerides, pancytopenia,	Corticosteroids, IVIG	Medical abortion at 19 wk	Health	Abortion	hemophagocytosis	Liu et al. (35)
22	24	SLE/CMV	Fever, elevated liver enzymes, ferritin, triglycerides, CD25, anaemia, thrombocytopenia	Methylprednisolone and IVIG treatment failed, remission with methylprednisolone and IVIG after delivery	29, Vaginal delivery for Prom	Health	Death	Normal	Liu et al. (35)
31	14	SLE	Fever, elevated liver enzymes, ferritin, CD25. Pancytopenia	Remission with corticosteroids, IVIG, Cyclosporin A	Medical abortion at 18 wk	Health	Abortion	hemophagocytosis	Liu et al. (35)
27	36	SLE	Fever, elevated liver enzymes, ferritin, triglycerides, CD25, pancytopenia	Remission with dexamethasone, IVIG, etoposide	Cesarean at 38 wk	Health	Health	Normal	Liu et al. (35)