Figure 3.
Social fear expression reduces the number and density of cFos-positive neurons exclusively in the dorsal hippocampus. (a,d) Mean number of cFos-ir cells in examined sections within the (a) dorsal and (d) ventral hippocampus of the granular cell layer of the dentate gyrus (DG), and the pyramidal cell layers of the cornu ammonis area 3 (CA3) and 1 (CA1). (b,e) Mean area of investigated layers in mm2. (c,f) Mean cell density (mean number of cFos-ir cells/mm3). SFC−, unconditioned control mice (n = 9); SFC+, conditioned socially fearful mice (n = 10). Data represent means + SEM. Statistical analysis was performed using a two-sample comparison test; p ** < 0.01.