Table 4.
Multivariate analyses for progression-free and overall survival using a Cox proportional hazards model with categorical variables.
| Variables | PFS | OS | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| HIPEC | ||||
| IDS | 1.00 | 1.00 | ||
| IDS + HIPEC | 0.60 (0.39-0.93) | 0.023 | 0.93 (0.33-2.64) | 0.896 |
ASA, American Society of Anesthesiologists; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; IDS, interval debulking surgery; HR, hazard ratio; PFS, progression-free survival; OS, overall survival.
Models were adjusted by age, ASA score, CA-125 level, FIGO stage, histology, residual disease after IDS, estimated blood loss, operative time, time interval between surgery and the start of adjuvant chemotherapy, chemotherapy regimen, surgical complexity score, BRCA mutation, and cycles of total chemotherapy.