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. 2022 Aug 2;11(15):2369. doi: 10.3390/cells11152369

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Changes in lipidic classes abundance induced by GPR17 silencing during OPC differentiation. The abundance of each lipid class in control conditions at different time points is reported (a). The kinetics of each lipid class after GPR17 silencing were analysed: (b) fatty acids, (c) ceramides, (d) LysoPC (lysophosphatidyl-cholines), (e) LysoPE (lysophosphatidyl-ethanolamines), (f) PCaa (diacyl-phosphatidyl-cholines), (g) PCae (acyl-alkyl-phosphatidyl-cholines), (h) PEaa (di-acyl-phosphatidyl-ethanolamines), (i) PEae (acyl-alkyl-phosphatidyl-ethanolamines), (j) PI (phosphatidyl-inositols), (k) PS (phosphatidyl-serines), (l) SM (sphingomyelins). n = 5 for each group. Kinetics: Two-way ANOVA followed by Tukey’s multiple comparison test. siGPR17: Two-way ANOVA followed by Sidak’s multiple comparison test. * p.adj < 0.05; ** p.adj < 0.01.