| BAP1 | BRCA1 associated protein 1 |
| CDC73 | cell division cycle 73 |
| CBX | Chromobox |
| CDK | Cyclin-dependent kinase |
| COMPASS | complex of proteins associated with SET1 |
| CTD | carboxyl-terminal domain |
| DDR | DNA damage response |
| DOTL1 | disruptor of telomere silencing 1 |
| DSBs | double strand breaks |
| DSS | dextran sodium sulfate |
| DUBs | deubiquitinating enzymes |
| E1 | ubiquitin-activating enzyme |
| E2 | ubiquitin-conjugating enzyme |
| E3 | ubiquitin ligase |
| EGR2 | early growth response 2 |
| ESCs | embryonic stem cells |
| FACT | facilitates chromatin transcription |
| H2AK119ub | histone H2A lysine 119 mono-ubiquitination |
| H2BK120ub | histone H2B lysine 120 mono-ubiquitination |
| iPSCs | induced pluripotent stem cells |
| PAF1 | RNA polymerase associated factor 1 |
| PCGF | Polycomb group RING finger |
| PHC | polyhomeotic homologue |
| PRC1 | Polycomb repressive complex 1 |
| cPRC1 | canonical PRC1 |
| ncPRC1 | non-canonical PRC1 |
| PRC2 | Polycomb repressive complex 2 |
| PR-DUB | Polycomb repressive deubiquitinase |
| PTM | post-transcriptional modification |
| SAGA | Spt-Ada-Gcn5 acetyltransferase |
| UBD | ubiquitin binding domain |
| USP | ubiquitin specific peptidase |
| UV | ultra-violet |
| WAC | WW domain-containing adaptor with coiled-coil |