Table 2.

The commonly used latent reversal agents.

Category	Examples	Mechanism of action	References
Cytokines or receptor agonists	IL2、IL7、IL15、TLR2,3	Reactivation of HIV expression	(Rochat et al., 2017) (Rasmussen et al., 2016)
Epigenetic modification enzyme inhibitors	HDACi、HMTi、DNMTi	Reactivation of HIV expression in vitro and in vivo	(Archin et al., 2017) (Bernhard et al., 2011)
Cell signal regulator	Prostra、BryostatinC	Activation of PKC pathway results in the release of NF-κB and pTEFb from inactive complex and increases pTEFb expression	(Wang et al., 2017) (Schwartz et al., 2017)
Others
Antioxidant	Auranofn (AF)	The mechanism of action is still unclear	(Chirullo et al., 2013)
AKT regulator	Disulfram		(Doyon et al., 2014)
Protein phosphatase 1	SMAPP1		(Smith et al., 2015) (Tyagi et al., 2015)