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. 2022 Jul 26;19(15):9095. doi: 10.3390/ijerph19159095

Table 6.

The blood biomarkers of the athletes in the two study groups at the three time points of the study.

Parameter
(Reference Value)
Group Time Point p1 Value p2 Value
T1 T2 T3
White Blood Cells
(×103/µL; 3.8–11)
HA 4.77 ± 0.97 4.51 ± 0.97 4.11 ± 1.04 0.774 0.129
NA 5.90 ± 1.50 6.11 ± 1.46 5.86 ± 1.34 0.235
Monocytes
(%; 2.5–10)
HA 7.72 ± 1.01 7.46 ± 1.21 7.47 ± 1.21 0.1364 0.268
NA 6.56 ± 1.67 6.14 ± 1. 13 7.54 ± 2.21 0.409
Lymphocytes
(%; 20–51)
HA 31.11 ± 9.14 31.31 ± 9.06 31.01 ± 8.61 0.124 0.182
NA 31.51 ± 7.50 31.35 ± 7.05 36.98 ± 7.91 0.471
Red Blood Cells
(×106 mL−1; 4.5–5.7)
HA 5.32 ± 0.33 5.31 ± 0.34 5.34 ± 0.26 0.354 0.103
NA 5.25 ± 0.40 5.22 ± 0.49 5.27 ± 0.33 0.249
Hemoglobin
(gxdL−1; 13–17)
HA 15.21 ± 1.11 15.53 ± 0.97 16.15 ± 0.85 a <0.05 <0.05
NA 15.33 ± 0.72 15.26 ± 0.85 14.97 ± 0.92 0.89
Hematocrit
(%; 40–50)
HA 45.77 ± 2.79 46.00 ± 2.53 46.14 ± 2.22 0.234 0.127
NA 46.01 ± 2.46 45.69 ± 2.25 45.57 ± 2.51 0.127
Reticulocyte Hemoglobin
(pg; 31.9–41.6)
HA 342.13 ± 10.08 353.12 ± 9.01 a 356.75 ± 10.67 a < 0.05 <0.05
NA 344.09 ± 7.11 343.09 ± 5.91 342.76 ± 9.13 0.236
Reticulocytes
(%; 0.6–2.4)
HA 1.32 ± 0.33 1.61 ± 0.41 a 1.65 ± 0.47 a <0.05 < 0.05
NA 1.30 ± 0.27 1.30 ± 0.91 1.29 ± 0.52 0.157
Erythropoietin
(mU/mL; 2.6–18.5)
HA 6.18 ± 1.59 6.69 ± 0.88 a 7.05 ± 1.13 a b <0.05 <0.05
NA 6.23 ± 1.34 6.21 ± 1.23 6.19 ± 1.65 0.265

Data are expressed as mean ± standard deviation. Differences between the groups and time points with p values < 0.05 were statistically significant, according to the Scheffé test: a, significant difference vs. T1; b, significant difference vs. T2; HA, hypoxic intervention group; NA control group; T1, baseline; T2, day 28; T3, day 56; p1, the analysis of variance (ANOVA) with repeated measures for each group separately; p2, the analysis of variance (ANOVA) with repeated measures of two factors to verify the existence of an interaction effect (condition × time).