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. 2022 Jul 28;15:888231. doi: 10.3389/fnmol.2022.888231

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Copyright © 2022 Kofler, Beltran-Quintero, Rugari, Zuccoli, Klotz and Escolar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neurocognitive development across multiple domains (A) without umbilical cord blood transplantation (UCBT) (case 1) and (C) after UCBT (case 2) using age-equivalent scores (i.e., developmental age). Head circumference (HC) development (B) without UCBT (case 1) and (D) after UCBT (case 2). The colored lines in panels (A,C) represent individual domains. The colored lines in panels (B,D) represent case 1 (blue) and case 2 (red). In all panels, the area between the gray lines represents typical development. ad, adaptive behavior; cog, cognitive; el, expressive language; fm, fine motor; gm, gross motor; rl, receptive language. P3, P5, P10, P25, P50, P75, P90, P95, and P97 represent percentiles (P).