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Experimental timeline. Cp, cisplatin; Cr, creatinine; het: heterozygous knockout for GPER1 gene; HO-1, heme oxygenase-1; homo, homozygous knockout for GPER1 gene; KIM-1, kidney injury molecule 1; NGAL, neutrophil gelatinase-associated lipocalin; Sal, saline; TUNEL, Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; WB, Western blotting; WT, wild-type. Created with BioRender.com.
