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. 2022 Jul 27;23(15):8295. doi: 10.3390/ijms23158295
CYP2D6 iso-enzyme 2D6 of the cytochrome P450 system
EFPIA European Federation of Pharmaceutical Industry Associations
EU European Union
IASP International Association for the Study of Pain
IMI Innovative Medicines Initiative (of the EU)
iPSC human induced pluripotent stem cell
MOR µ-opioid receptor
NeuPSIG Neuropathic Pain Special Interest Group (of the IASP)
PK pharmacokinetic(s)
SmPC Summary of Product Characteristics
Tmax time to peak plasma concentration
t1/2 elimination half-life
Nomenclature
BioPain a subproject of the IMI-PainCare project, which is a consortium of researchers from academia, hospitals, small-medium sized enterprises, patient organizations, pain societies and the pharmaceutical industry that combines and mutually shares expertise. Its goal is fulfilment of the objectives of Call H2020-JTI-IMI2-10, topic 3.
Call H2020-JTI-IMI2-10, topic 3 a request for research proposals issued by the Innovative Medicines Initiative of the European Union and EFPIA in the framework of the Horizon 2020 pro-gramme.