Figure 2.

Overview of the most distinct age-associated microglial populations and their transcriptomic signatures revealed through transcriptional profiling of murine and human microglia using single-cell RNA sequencing. Microglial subsets are represented with superscript numbers as described in the studies of ¹ Hammond et al. [15], ² Masuda et al. [16], ³ Sankowski et al. [18], ⁴ Li et al. [39], ⁵ Matcovitch-Natan et al. [40]. ↑ denotes transcriptomic upregulation. Figure created with BioRender.com (accessed on 18 June 2022).