Table 11.

Overview case-reports.

Source	Country	Treatment Indication	Beta-Blocker Type	Dosage	Blood Glucose	Heart Rate (Beats per Minute)
Sullo MG, 2015 [66]	Italy	Unspecified tachycardia	Nebivolol	5 mg per day	30 mg/dL	x
Stevens TP, 1995 [67]	United States	Hypertension	Labetalol	150 mg two times per day	1.7 mmol/L (30 mg/dL)	111 after birth 100 in transit to tertiary referral center 100–120 (resting heart rate)
Klarr JM, 1994 [68]	United States	Hypertension prior to cesarean section	Labetalol	Single 30 mg dosage	31 mg/dL (twin A) 37 mg/dL (twin B)	<80 (both twins)
Haraldsson A, 1989 [69]	The Netherlands	Hypertension prior to cesarean section	Labetalol	50 mg/hour	Not described in article, but intravenous glucose was given	Severe bradycardia immediately after delivery. On admission the heart rate was 140
Haraldsson A, 1989 [70]	The Netherlands	Pregnancy induced hypertension	Labetalol	600 mg (200 mg 3 times per day)	1.2 mmol/l	<80 after delivery, 148 later
Schmimmel MS, 1989 [71]	Israel	Postpartum hypertension	Atenolol	100 mg daily (50 mg two times per day)	x	80
Fox RE, 1985 [72]	United States	Hypertension	Nadolol	20 mg once per day	20 mg/dl	136 after birth 112 at 4.5 h of age 1 >135 at 4 days of age
Woods DL, 1982 [73]	South Africa	Uncontrolled hypertension	Atenolol	100 mg daily	2–5 mmol/L (45 mg/100 mL)	138
Bott-Kanner G,1978 [74]	Israel	Chronic hypertension	Propranolol	160 --> 60 mg/day 2 (first pregnancy) 120 --> stop (second pregnancy)	37 mg/dL (first pregnancy) 75 mg/dL after birth, 87 mg/dL next day (second pregnancy)	150 (first pregnancy) 140 (second pregnancy)
Sabom MB, 1978 [75]	United States	Idiopathic Hypertrophic subaortic stenosis	Propranolol	60 mg 4 times per day, discontinued upon admission	25–45 mg/100 ml	Sinus bradycardia (heart rate not mentioned)
Datta S, 1978 [76]	United States	Idiopathic Hypertrophic subaortic stenosis	Propranolol	80 mg daily	No hypoglycemia	110–120, with a short period of 80 during sleep
Habib A, 1977 [77]	United States	Hyperthyroidism and congestive heart failure (case 1), supraventricular tachycardia (case 2 and 3) and hyperthyroidism (case 4)	Propranolol	10 mg 4 times per day (case 1, 2 and 3), 10 mg two times per day (case 4) 3	20 mg/dL (case 1) 30 mg/dL (case 2) 25 mg/dL at one hour of age and 5 mg/dL at two hours of age (case 3) 25–45 mg/dL (case 4)	80 within one hour of delivery (case 1) 4 80–90 5 (case 2) 100–120 6 (case 3) 80–90, frequently during first 24 h of life (case 4)
Cottrill CM, 1977 [78]	United States	Chronic atrial tachycardia	Propranolol	160 mg per day (40 mg 4 times per day) 7	Too low to be detected by the Dextrostix method	40 at birth, later it varied between 100 and 165
Gladstone GR, 1975 [79]	United States	Essential hypertension	Propranolol	240 mg per Day decreased to 160 mg per Day 8	11 mg/dL	70–90 during first day of life. Rose with stimulation to 120/minute. Was 120–130/minute on day 5
Fiddler GI, 1974 [80]	Scotland	Hypertrophic Obstructive cardiomyopathy	Propranolol	30 mg 3 times per day	12 mg/100 mL	x

¹ The heart rate remained low for 72 h, and frequent short episodes of bradycardia occurred that were not associated with apnea and that resolved spontaneously [72]. ² At the time of conception, the mother was placed on a regimen of 160 mg/day. Three weeks prior to term, the propranolol dosage was reduced to 60 mg/day in preparation for the delivery [74]. ³ In case 1, the mother was receiving propranolol 20 mg for times a day at time of delivery [77]. ⁴ The bradycardia persisted for most of the first 36 h of life, and the heart rate remained between 100 to 120 per minute for most of the second 36 h [77]. ⁵ Frequent episodes of bradycardia during the first 24 h of life and occasional episodes over the next 48 h [77]. ⁶ The infant had occasional episodes of bradycardia (heart rate 80 to 90/minute) during the first 48 h of life, but his heart rate generally ranged between 100 to 120/minute [77]. ⁷ The day prior to the Cesarean section, she received 60 mg propranolol every six hours and 60 mg was given orally six hours before surgery; an additional 3 mg was given intravenously one hour before the operation [78]. ⁸ The mother was taking 240 mg/day at the time of conception. The dose was decreased to 160 mg/day in the fourth month of pregnancy [79].