Table 2.
Treatment assignment
| Treatment | Product | Metaphylaxis dosage | Post-metpahylactic interval, d | Therapeutic dosage | Post-treatment interval, d | Pens |
|---|---|---|---|---|---|---|
| TCD1 | Tulathromycin3 | 2.5 mg/kg | 7 | N/A | N/A | 10 |
| Ceftiofur crystalline free acid4 | N/A | N/A | 6.6 mg/kg | 5 | ||
| Danofloxacin5 | N/A | N/A | 8 mg/kg | 3 | ||
| TFFE2 | Tildipirosin6 | 4 mg/kg | 7 | N/A | N/A | 10 |
| Florfenicol-flunixin meglumine7 | N/A | N/A | 40 mg/kg florfenicol; 2.2 mg/kg flunixin meglumine |
5 | ||
| Enrofloxacin8 | N/A | N/A | 12.5 mg/kg | 3 |
Metaphylaxis with tulathromycin (2.5 mg/kg BW), followed by first BRD treatment with ceftiofur crystalline acid (6.6 mg/kg BW), followed by second BRD treatment with danofloxacin (8 mg/kg BW).
Metaphylaxis with tildipirosin (4 mg/kg BW), followed by first BRD treatment with florfenicol-flunixin meglumine (40 mg/kg BW; 2.2 mg/kg BW), followed by second BRD treatment with enrofloxacin (12.5 mg/kg BW).
Draxxin, Zoetis, Parsippany, NJ.
Excede, Zoetis, Parsippany, NJ.
Advocin, Zoetis, Parsippany, NJ.
Zuprevo, Merck Animal Health, Madison, NJ.
Resflor Gold, Merck Animal Health, Madison, NJ.
Baytril, Elanco Animal Health, Greenfield, IN.