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. 2022 Jul 28;23(15):8318. doi: 10.3390/ijms23158318

Table 1.

Effect of adropin on metabolic parameters.

Organ/Systems/Condition Effect Reference
Liver Increases the expression of hepatic lipogenic genes and PPARγ [14]
Cardiovascular system Increases angiogenesis, blood flow, capillary density, and protects endothelial cells [23]
Improves cardiac function and coronary flow [77]
Diabetes mellitus Low adropin level increases the risk of chronic complications of diabetes [63,64,65]
Stimulates insulin signal pathways by promoting Akt phosphorylation [20]
Fat Suppresses lipid accumulation [78,79]
Inflammation Inhibits TNF-α [80]