Table 3.
Immune profile of semen collected from the studied groups.
| Excellent Motility (n = 43) | High Motility (n = 40) | Acceptable Motility (n = 41) | |
|---|---|---|---|
| IL-1 α [pg/mL] | 4.30 (1.63; 22.87) | 5.05 (2.50; 22.48) | 10.44 (2.80; 26.89) **EM; **HM |
| IL-1 β [pg/mL] | 8.82 (6.11; 10.94) | 11.08 (8.40; 16.76) | 13.10 (8.78; 32.83) *EM |
| IL-2 [pg/mL] | 0.42 (0.00; 1.00) | 2.43 (0.00; 7.56) **EM | 4.51 (0.00; 8.29) ***EM; **HM |
| IL-4 [pg/mL] | 1.72 (1.57; 2.03) | 1.95 (1.57; 2.23) | 2.03 (1.72; 2.26) |
| IL-6 [pg/mL] | 7.45 (2.72; 12.92) | 10.76 (3.92; 15.02) | 14.27 (6.55; 26.08) **EM; *HM |
| IL-8 [pg/mL] | 715.50 (580.2; 1317) | 891.90 (594.60; 1351) | 1236.00 (699.20; 1351) *EM |
| IL-10 [pg/mL] | 11.38 (10.22; 19.23) | 15.54 (14.20; 20.07) | 21.08 (13.91; 57.47) *EM |
| VEGF [pg/mL] | 3200.00 (2168.00; 3349.00) | 3132.00 (2597.00; 3749.00) | 2957.00 (2449.00; 3075.00) |
| IFN-γ [pg/mL] | 0.47 (0.00; 0.68) | 2.86 (0.00; 3.12) **EM | 2.99 (0.00; 24.71) **EM |
| TNF-α [pg/mL] | 0.15 (0.00; 0.37) | 0.26 (0.00; 0.86) | 6.56 (0.00; 8.24) ***EM; ***HM |
| MCP-1 [pg/mL] | 1414.00 (776.60; 1596.00) | 1596.00 (1104.00; 1720.00) | 1596.00 (1260.00; 1705.00) |
| EGF [pg/mL] | 1197.00 (1039.00; 1500.00) | 1197.00 (1001.00; 1444.00) | 1200.00 (1020.00; 1450.00) |
Values are represented as median (25th; 75th percentile). * p < 0.05; ** p < 0.01; *** p < 0.001. EM—versus excellent motility group; HM—versus high motility group. IL-1 α—interleukin-1 alpha, IL-1 β—interleukin-1 beta, IL-2—interleukin-2, IL-6—interleukin-6, IL-8—interleukin-8, IL-10—interleukin-10, VEGF—vascular endothelial growth factor, IFN-γ—interferon gamma, TNF-α—tumor necrosis factor alpha, MCP-1—monocyte chemoattractant protein-1, EGF—epidermal growth factor.