Table 2.
B and Tregs populations comparisons. The data refers to Figure 1 extracted percentages (mean ± standard deviation), excluding controls, and p values were calculated applying two-way ANOVA corrected with Tukey: a: comparison among Onset and recovered children; b: comparison among onset and long; and c: comparison among long and recovered.
Lymphocyte Populations | Onset | Recovered | Long | p-Values | ||
---|---|---|---|---|---|---|
a | b | c | ||||
IgD−CD27+ memory B cells | 0.3 ± 0.3 | 0.4 ± 0.4 | 0.4 ± 0.6 | 1.0 | 1.0 | 1.0 |
IgD+CD27− naïve B cells | 3.9 ± 3.9 | 1.1 ± 1.4 | 1.2 ± 1.3 | <0.0001 | <0.0001 | 1.0 |
IgD−IgM− B cells | 0.5 ± 0.4 | 1.0 ± 1.6 | 1.0 ± 1.3 | 0.6 | 0.5 | 1.0 |
IgD+IgM+ B cells | 3.4 ± 6.4 | 0.4 ± 0.4 | 0.7 ± 1.2 | <0.0001 | <0.0001 | 1.0 |
IgM+CD27−CD38dim B cells | 2.2 ± 2.5 | 0.2 ± 0.3 | 0.4 ± 0.8 | <0.0001 | <0.0001 | 0.8 |
CD25highFOXP3+ Treg | 1.9 ± 0.8 | 1.3 ± 0.5 | 1.5 ± 0.8 | <0.0001 | 0.0004 | 0.14 |
Inducible Tregs | 0.5 ± 0.5 | 0.7 ± 0.4 | 0.8 ± 0.5 | 0.5 | 0.1 | 0.9 |
Natural Tregs | 0.4 ± 0.4 | 0.04 ± 0.07 | 0.1 ± 0.4 | 0.0005 | 0.0026 | 0.8 |
Suppressor T regs | 0.2 ± 0.3 | 0.3 ± 0.2 | 0.2 ± 0.2 | 0.7 | 0.8 | 0.9 |