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. 2022 Aug 6;23(15):8751. doi: 10.3390/ijms23158751

Table 2.

miRNAs dysregulated in CD across various tissue samples.

miRNAs Upregulated miRNAs Downregulated References
Ileal/colonic tissue miRs-16, -21(-3p), -23b, -31(-3p), -106a, -146a-3p, -155(-5p), -191, -195, -223, -594 miRs-19b, -375, -629 [13,14,32,33]
Peripheral blood miRs-29, 101, 146-5p, -146b-5p -199a-5p, -340, -362-3p, -375, -532-3p, -598, -642, miRplus-E1271 miRs-21, -31, -146a, -149, miRplus-F1065 [14,15,16,17,33]
Fecal matter miRs-15a-5p, -16-5p, -24-3p, -27a-3p, -128-3p, -142-5p, -155, -223(-3p and -5p), -3074-5p miRs-10a-5p, -10b-5p, -141-3p, -192-5p, -200a-3p, -375, -378-3p, let-7g-5p [19,34]
Saliva miRs-26a, -101 [14]

Sample types listed include intestinal biopsies from both the ileum and colon, peripheral blood samples, fecal matter, and saliva samples from CD patients (vs. healthy sample controls).