Table 2.
miRNAs Upregulated | miRNAs Downregulated | References | |
---|---|---|---|
Ileal/colonic tissue | miRs-16, -21(-3p), -23b, -31(-3p), -106a, -146a-3p, -155(-5p), -191, -195, -223, -594 | miRs-19b, -375, -629 | [13,14,32,33] |
Peripheral blood | miRs-29, 101, 146-5p, -146b-5p -199a-5p, -340, -362-3p, -375, -532-3p, -598, -642, miRplus-E1271 | miRs-21, -31, -146a, -149, miRplus-F1065 | [14,15,16,17,33] |
Fecal matter | miRs-15a-5p, -16-5p, -24-3p, -27a-3p, -128-3p, -142-5p, -155, -223(-3p and -5p), -3074-5p | miRs-10a-5p, -10b-5p, -141-3p, -192-5p, -200a-3p, -375, -378-3p, let-7g-5p | [19,34] |
Saliva | miRs-26a, -101 | [14] |
Sample types listed include intestinal biopsies from both the ileum and colon, peripheral blood samples, fecal matter, and saliva samples from CD patients (vs. healthy sample controls).