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. 2022 Jul 29;23(15):8373. doi: 10.3390/ijms23158373

Figure 6.

Figure 6

ANP treatment alleviated mitochondrial damage after IRI in HFD hearts. (A) Representative electron micrographs of heart sections after IRI with or without ANP. Each pair of electron micrographs displayed a set at lower magnification (top; scale bar, 2.0 μm) and higher magnification (bottom; scale bar, 20.0 μm). (B) Number of damaged mitochondria after IRI. (C) Representative immunoblots for cleaved and total caspase 3 from cardiac lysates after IRI. (D) Densitometric quantitation normalized to the level of cleaved/total caspase 3 expression in NFD hearts after IRI is shown (n = 5 each). * p < 0.05 and ** p < 0.01 versus HFD.