Figure 15.
Ro31-8220 reversed (−)BPAP-induced [3H]dopamine release in rat striatum. For the experimental procedure, see Figure 2A. (−)BPAP was added to striatal slices from fraction 8 in a concentration of 10−12 mol/L in the presence and absence of Ro31-8220. When used, Ro31-8220 was added to striatal slices from fraction 1 in a concentration of 1 µmol/L and drugs were maintained throughout the experiment. One-way ANOVA followed by the Dunnett’s test, F(3,21) = 9.235, p < 0.001, control vs. (−)BPAP effect # p < 0.05. Student t-statistics for two-means, (−)BPAP vs. (−)BPAP plus Ro31-8220 effect * p = 0.001, mean ± S.E.M., n = 3-8.