Figure 17.
Phorbol 12-myristate 13-acetate (PMA) potentiated the (−)BPAP-stimulated [3H]dopamine release in rat striatum. For the experimental procedure, see Figure 2A. (−)BPAP was added to striatal slices from fraction 8 in a concentration of 10−12 mol/L. PMA was added to striatal slices from fraction 12 at a concentration of 1 µmol/L, and drugs were maintained throughout the experiment. One-way ANOVA followed by the Dunnet’s test, F(3,28) = 82.75, p < 0.0001, * p < 0.05. Student t-statistics for two-means, PMA vs. PMA plus (−)BPAP effect # p < 0.0001, mean ± S.E.M., n = 8.