Figure 19.
N-Ethylmaleimide (NEM) NEM potentiated the (−)BPAP-stimulated [3H]dopamine release in rat striatum. For the experimental procedure, see Figure 2A. (−)BPAP was added to the slices from fraction 8 in a concentration of 10−12 mol/L. NEM was added to the slices from fraction 12 in a concentration of 30 µmol/L and drugs were maintained throughout the experiment. One-way ANOVA followed by the Dunnett’s test, F(3,26) = 8.740, p = 0.048, control vs. NEM and (−)BPAP effect # p < 0.05. Student t-statistics for two-means, control vs. NEM effect * p < 0.01, NEM vs. NEM and (−)BPAP effect * p < 0.05, (−)BPAP vs. (−)BPAP/NEM effect * p < 0.05, mean ± S.E.M., n = 7-8.