Table 2.
Comparison of patient characteristics in FGR and SGA cohorts.
| Cerebral Dopplers between ISUOG Grouping | SGA Mean ± SEM (n = 30) |
FGR Mean ± SEM (n = 51) |
p Value |
|---|---|---|---|
| Mean MCA PI centile † | 41.36% ± 4.86% | 41.05% ± 4.46% | 0.787 |
| Mean ACA PI centile † | 37.80% ± 5.75% | 32.38% ± 4.26% | 0.377 |
| Mean PCA PI centile † | 44.00% ± 4.51% | 34.93% ± 4.25% | 0.104 |
| Mean UA PI centile † | 63.47% ± 3.70% | 77.41% ± 3.18% | 0.0008 *** |
| Clinical Variables | |||
| GA at Analysis (wks) † | 35.82 ± 0.27 | 35.94 ± 0.22 | 0.710 |
| GA at Delivery (wks) † | 37.84 ± 0.22 | 37.29 ± 0.23 | 0.186 |
| Birthweight (g) ‡ | 2636 ± 59.86 | 2247 ± 65.06 | <0.0001 *** |
| Cesarean Section Rate § | 4/26 (15.38%) | 10/37 (27.03%) | 0.362 |
| Fenton Birthweight (%) ‡ | 20.61% ± 2.88% | 6.91% ± 0.78% | <0.0001 *** |
| NICU Admission § | 4/22 (18.18%) | 13/36 (36.11%) | 0.234 |
Mann-Whitney U † or independent samples t-tests ‡ were used following a normality test. Fisher’s exact tests § were used for categorical variables. Because standard deviation equations were not published with the VA PI nomogram, we are unable to calculate PI centile for VA Dopplers. Abbreviations: SEM: standard error of the mean; MCA: middle cerebral artery; PI: pulsatility index; ACA: anterior cerebral artery; PCA: posterior cerebral artery; UA: umbilical artery; GA: gestational age; wks: weeks; NICU: neonatal intensive care unit. “* indicates statistical significance (* p < 0.05; ** p < 0.01; *** p < 0.001).”