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. 2022 Jul 29;11(15):4426. doi: 10.3390/jcm11154426

Figure 4.

Figure 4

Differentially expressed exosomal miRNAs between esophageal epithelial cell and esophageal squamous cell carcinoma cell lines. (A) Volcano plots of differentially expressed exosomal miRNAs. Colored circles represent miRNAs significant at |fold change (FC)| ≥ 2 and p < 0.05. Orange dot, up-regulated; blue dot, down-regulated. (B) Heatmap of hierarchical clustering based on 14 differentially expressed exosomal miRNAs (five up-regulated and nine down-regulated). Samples with similar miRNA expression were grouped.