Figure 3.

Effects of dietary CSO and MSO on progression of atherosclerosis in LDLR-KO mice. Mice (n = 12/group) were fed a Western diet supplemented with 5% (w/w) CSO, MSO, or none (control) for 12 weeks. (A) Representative en face Sudan IV staining of aorta (left) and quantitative analysis of Sudan IV-positive plaque area of aorta (right). (B) Representative Oil-Red O staining of aorta sinus (left) and quantitative analysis of cross-sectional Oil Red O-positive area of aortic sinus (right). CSO: conventional soybean oil, MSO: modified soybean oil. Values represent the mean ± SEM. * p < 0.05 compared with the control Western diet; ^# p < 0.05 compared with the CSO diet.