Table 2.
Effect of CSO and MSO diets on plasma lipid levels in LDLR-KO mice.
| Lipids | Control | CSO Diet | MSO Diet |
|---|---|---|---|
| Week 0 | |||
| TC | 251.6 ± 6.5 | 227.7 ± 21.3 | 244.5 ± 7.2 |
| FC | 84.9 ± 4.2 | 78.6 ± 2 | 83.4 ± 2.2 |
| PL | 239.1 ± 8.7 | 219.6 ± 7.9 | 255.7 ± 8.8 |
| TG | 178.3 ± 11.9 | 156.9 ± 6.2 | 161.9 ± 6.5 |
| Week 3 | |||
| TC | 783.8 ± 12.1 | 737.2 ± 12.6 * | 813 ± 13.5 ### |
| FC | 211.7 ± 4.6 | 190.4 ± 6.2 * | 211 ± 6.4 ## |
| PL | 666 ± 15.8 | 590.9 ± 17.5 ** | 675.6 ± 16.9 ## |
| TG | 223.3 ± 16.9 | 219.5 ± 20.7 | 282 ± 25.2 |
| Week 6 | |||
| TC | 882.6 ± 13 | 764.9 ± 13.6 **** | 859.6 ± 18.1 ### |
| FC | 237.4 ± 3.8 | 178 ± 5.7 **** | 229.9 ± 5.7 #### |
| PL | 712.9 ± 11.8 | 565.4 ± 12.8 **** | 684.2 ± 17.1 #### |
| TG | 224.1 ± 17 | 155 ± 19.8 | 259.0 ± 40.4 # |
| Week 9 | |||
| TC | 880.8 ± 13.2 | 711.4 ± 22.9 **** | 839.6 ± 17.3 #### |
| FC | 250.6 ± 4.7 | 166.3 ± 7.5 **** | 231.2 ± 6.8 #### |
| PL | 711.6 ± 10.8 | 546.1 ± 16.9 **** | 671.7 ± 14.6 #### |
| TG | 199.5 ± 15.1 | 93.7 ± 13.8 * | 207.6 ± 37.8 ## |
| Week 12 | |||
| TC | 780.9 ± 14.6 | 735.6 ± 171.1 | 806.7 ± 13.7 ## |
| FC | 234.3 ± 13.2 | 185 ± 7.6 **** | 219.2 ± 7.8 ## |
| PL | 727 ± 13.2 | 653.2 ± 27.9 * | 708.2 ± 17.9 |
| TG | 179.3 ± 20 | 175.3 ± 26.7 | 204.1 ± 33.1 |
Mice (n = 12/group) were fed a Western diet supplemented with 5% (w/w) CSO, MSO, or none (control) for 12 weeks. CSO: conventional soybean oil, MSO: modified soybean oil. TC: total cholesterol, FC: free cholesterol, PL: phospholipid, TG: triglyceride. Values represent the mean ± SEM. * p < 0.05, ** p < 0.01; **** p < 0.0001 compared with control. # p < 0.05; ## p < 0.01; ### p < 0.001; #### p < 0.0001, compared with CSO diet.