Table 2.

Blood gas, glucose and lactate concentration before, 2 h, 4 h and 6 h after ischemia, followed by daily until day 7 in near term fetal sheep in the sham control (n = 8), ischemia-vehicle (n = 7) and ischemia-hAEC groups (n = 6). * p < 0.05 versus sham control, ^# p < 0.05 versus ischemia-vehicle.

Group		Baseline	2 h	4 h	6 h	1 d	2 d	3 d	4 d	5 d	6 d	7 d
Sham-control	pH	7.38 ± 0.01	7.38 ± 0.01	7.38 ± 0.01	7.39 ± 0.01	7.38 ± 0.01	7.37 ± 0.01	7.37 ± 0.01	7.36 ± 0.01	7.35 ± 0.01	7.34 ± 0.01	7.35 ± 0.01
Ischemia-vehicle		7.4 ± 0.01	7.39 ± 0.01	7.41 ± 0.01	7.40 ± 0.01	7.38 ± 0.02	7.39 ± 0.01	7.37 ± 0.01	7.37 ± 0.01	7.37 ± 0.01	7.37 ± 0.01	7.37 ± 0.01
Ischemia-hAEC		7.34 ± 0.03	7.32 ± 0.03 *	7.33 ± 0.03 #	7.35 ± 0.02 #	7.35 ± 0.02	7.35 ± 0.01	7.34 ± 0.01	7.31 ± 0.01 *,#	7.33 ± 0.01	7.33 ± 0.02	7.35 ± 0.01
Sham-control	pCO2	48.8 ± 4.3	47.4 ± 2.8	48.8 ± 1.5	47.3 ± 0.1	47.2 ± 1.1	48.3 ± 1.3	46.4 ± 1.2	48.7 ± 0.7	50.3 ± 0.5	49.5 ± 1.8	46.8 ± 0.1
Ischemia-vehicle		44.6 ± 1.4	42.6 ± 1.6	43.4 ± 1.4	44.9 ± 1.9	44.4 ± 2.7	44.1 ± 1.3	44.5 ± 1.9	45.5 ± 1.2	46.7 ± 1.9	46.7 ± 1.6	49.4 ± 1.9 *
Ischemia-hAEC		55.3 ± 1.3 *,#	52.3 ± 1.3 *,#	53.1 ± 1.2 *,#	54.0 ± 1.0 *,#	54.2 ± 0.8 *,#	52.8 ± 1.3 #	53 ± 1.3 #	54.2 ± 1.2 #	51.8 ± 1.4	55.5 ± 1.2 #	53.9 ± 1.0 *
Sham-control	pO2	21.4 ± 0.3	21.6 ± 1.2	21.2 ± 1.1	20.9 ± 1.2	20.1 ± 1.3	22.6 ± 3.1	22.2 ± 2.9	22.9 ± 2.2	24.3 ± 3.6	26 ± 2.7	23.7 ± 2.2
Ischemia-vehicle		26.0 ± 1.1	25.8 ± 1.2	25.9 ± 1.3	25.4 ±1.9	25.0 ± 2.0	24.6 ±1.5	26.7 ± 1.6	25.5 ± 1.9	26.0 ± 1.9	24.7 ± 1.4	22.9 ± 1.1
Ischemia-hAEC		22.9 ± 1.3	20.6 ± 1.2	20.1 ± 0.6	20.6 ± 1.0	19.1 ± 1.2	19.5 ± 1.4	26.9 ± 1.0	26.6 ± 0.9	24.8 ± 1.2	24.3 ± 1.2	24.2 ± 0.8
Sham-control	Lactate	0.9 ± 0.2	1.0 ± 0.2	1.2 ± 0.0	1.2 ± 0.1	1.0 ± 0.1	1.0 ± 0.2	0.9 ±0.4	1.0 ± 0.2	0.8 ± 0.2	0.8 ± 0.3	0.8 ± 0.4
Ischemia-vehicle		1.1 ± 0.1	2.4 ± 0.5 *	2.3 ± 0.5 *	2.1 ± 0.4 *	4.7 ± 1.1 *	0.9 ± 0.1	1.0 ± 0.1	1.1 ± 0.1	1.1 ± 0.1	1.1 ± 0.1	1.2 ± 0.1
Ischemia-hAEC		1.2 ± 0.1	3.8 ± 0.7 *	3.9 ± 0.8 *	3.5 ± 0.7 *	2.5 ± 0.7 *	2.6 ± 0.7 *	0.8 ± 0.1	0.8 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1
Sham-control	Glucose	0.6 ± 0.3	0.6 ± 0.2	0.8 ± 0.2	0.8 ± 0.2	0.8 ± 0.2	0.7 ± 0.1	0.6 ± 0.3	0.6 ± 0.1	0.6 ± 0.2	0.6 ± 0.1	0.5 ± 0.2
Ischemia-vehicle		1.0 ± 0.1	1.3 ± 0.1 *	1.3 ± 0.1 *	1.3 ± 0.1 *	1.5 ± 0.1 *	0.9 ± 0.1	0.9 ± 0.1	0.9 ± 0.1	1.0 ± 0.1	1.0 ± 0.1	1.0 ± 0.1
Ischemia-hAEC		1.0 ± 0.1	1.6 ± 0.1 *	1.4 ± 0.1 *	1.4 ± 0.1 *	1.1 ± 0.2	1.3 ± 0.3 *	0.8 ± 0.1	0.8 ± 0.1	0.9 ± 0.1	0.8 ± 0.1	0.9 ± 0.1