Table 2.
No. | Author (Year) | Age (y) | Sex | Localisation | Symptoms | Surgery | RTX Dose (cGy) | CTH | Relapse in the Larynx | Progression to Systemic PCM | Death | PFS (mo) | OS (mo) | Ref. |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Lu and Zhang (2020) | 57 | F | 1 | 1 | 1 | 5000 | 0 | 0 | 0 | 0 | 8 | 8 | [9] |
2 | Tanrivermis Sayit et al. (2020) | 74 | F | 4 | 1, 7 | 0 | Y | 1 | 0 | 0 | 0 | 3 | 3 | [10] |
3 | Ong et al. (2020) | 55 | M | 1 | NA | NA | NA | NA | NA | NA | NA | NA | NA | [11] |
4 | Brandt et al. (2020) | 54 | F | 1 | 1, 2 | 0 | 5000 | 0 | 0 | 0 | 0 | 18 | 18 | [4] |
5 | Ge et al. (2018) | 46 | M | 1 | 3, 6 | 0 | 5500 | 1 | 0 | 0 | 0 | 60 | 60 | [3] |
6 | Krebs et al. (2017) | 77 | M | 3 | 4, 5 | 0 | 4600 | 0 | 0 | 0 | 0 | 26 | 26 | [12] |
7 | Wang et al. (2015) | 43 | M | 6 | 1, 2, 4 | 1 | N | 0 | 1 | 1 | 0 | 12 | 60 | [13] |
8 | Haser et al. (2015) | 72 | M | 5 | 1, 4, 8 | 0 | Y | 0 | 0 | 0 | 0 | 12 | 12 | [14] |
9 | Pino et al. (2015) | 65 | M | 1 | 1, 2, 7 | 1 | 4600 | 0 | 0 | 0 | 0 | 54 | 54 | [15] |
10 | Xing et al. (2015) | 47 | F | 4 | 1 | 1 | 5000 | 0 | 0 | 0 | 0 | 18 | 18 | [16] |
11 | Abrari et al. (2014) | 56 | M | 2 | 4,10 | 0 | Y | 0 | 0 | 0 | 0 | NA | NA | [17] |
12 | Loyo et al. (2013) | 80 | F | 4 | 1, 2, 4, 8 | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [18] |
13 | Ghatak et al. (2013) | 29 | F | 4 | 1, 4, 7 | 0 | 5000 | 0 | 0 | 0 | 0 | 16 | 16 | [19] |
14 | Ramírez-Anguiano et al. (2012) | 57 | M | 5 | 2, 4, 8 | 0 | 5400 | 0 | 0 | 0 | 0 | 18 | 18 | [20] |
15 | Pinto et al. (2012) | 49 | F | 1 | 2 | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [21] |
16 | Kim et al. (2012) | 58 | M | 1 | 0 | 1 | N | 0 | 0 | 0 | 0 | 24 | 24 | [22] |
17 | Ravo et al. (2012) | 56 | M | 1 | 1, 4, 7 | 1 | 5000 | 0 | 0 | 0 | 0 | 5 | 5 | [23] |
18 | De Zoysa et al. (2012) | 62 | F | 2 | 2 | 0 | Y | 0 | 0 | 0 | 0 | 2 | 2 | [24] |
19 | Pichi et al. (2011) | 73 | M | 5 | 1, 4 | 0 | 4000 | 0 | 0 | 1 | 1 | 12 | 24 | [25] |
20 | Zhang et al. (2010) | 56 | F | 1 | 1, 2 | 1 | N | 0 | 0 | 0 | 0 | 24 | 24 | [26] |
21 | González Guijarro et al. (2010) | 11 | M | 4 | 2 | 1 | 4500 | 0 | 0 | 0 | 0 | 36 | 36 | [27] |
22 | Pratibha et al. (2009) | 49 | M | 6 | 1 | 0 | 4400 | 0 | 0 | 0 | 0 | 6 | 6 | [28] |
23 | Fernández-Aceñero et al. (2009) | 42 | F | 1 | 2, 7 | 0 | Y | 0 | 0 | 0 | 0 | NA | NA | [29] |
24 | Iseri et al. (2009) | 46 | F | 1 | NA | 1 | Y | 1 | 0 | 0 | 0 | 24 | 24 | [30] |
25 | Bilić et al. (2009) | 64 | M | 1 | NA | 0 | N | 1 | NA | NA | NA | 21 | 21 | [31] |
26 | Rutherford et al. (2009) | 13 | F | 3 | NA | 1 | Y | 0 | 0 | 0 | NA | 1 | 1 | [32] |
27 | Vanan et al. (2009) | 16 | F | 2 | 1 | 0 | 5040 | 0 | 0 | 0 | 0 | 12 | 12 | [33] |
28 | Straetmans and Stokroos (2008) | 57 | M | 1 | NA | 1 | 5000 | 0 | 1 | 0 | 0 | 2 | 24 | [34] |
29 | Ozbilean Acar et al. (2008) | 43 | F | 2 | NA | 1 | N | 0 | 0 | 0 | 0 | 24 | 24 | [35] |
30 | Lewis et al. (2007) | 71 | M | 1 | 1 | 1 | Y | 0 | 0 | 0 | 0 | 24 | 24 | [36] |
31 | Kusunoki et al. (2007) | 76 | F | 1 | 0 | 0 | N | 0 | 0 | 0 | 0 | 6 | 6 | [37] |
32 | Velez et al. (2007) | 64 | M | 4 | 1 | 1 | Y | 0 | 0 | 0 | 0 | 36 | 36 | [38] |
33 | Nakashima et al. (2006) | 39 | M | 1 | 0 | 1 | 6000 | 0 | 0 | 0 | 0 | 72 | 72 | [39] |
34 | Nakashima et al. (2006) | 59 | M | 1 | 0 | 1 | N | 0 | 0 | 0 | 0 | 180 | 180 | [39] |
35 | Mackiewicz-Nartowicz et al. (2005) | 79 | F | 2 | 1 | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [40] |
36 | Coskun et al. (2005) | NA | NA | NA | NA | 0 | Y | 0 | 0 | NA | 0 | NA | NA | [41] |
37 | Chao et al. (2005) | 60 | M | 1 | 5, 1 | 0 | 5000 | 0 | 0 | 0 | 1 | 37 | 37 | [42] |
38 | Sakiyama et al. (2005) | 47 | F | 3 | 0 | 0 | 5000 | 1 | 1 | 0 | 0 | 4 | 88 | [43] |
39 | Yavas et al. (2004) | 43 | F | 2 | 1 | 0 | N | 0 | 0 | 0 | 0 | NA | NA | [44] |
40 | Michalaki et al. (2003) | 46 | F | NA | NA | 0 | 4500 | 0 | 0 | 0 | 0 | 49 | 49 | [45] |
41 | Michalaki et al. (2003) | 59 | M | NA | NA | 0 | 4000 | 0 | 0 | 0 | 0 | 67 | 67 | [45] |
42 | Kamijo et al. (2002) | 84 | M | 1 | 1 | 1 | 6000 | 0 | 0 | 0 | 0 | 24 | 24 | [46] |
43 | Takeda et al. (2002) | 53 | F | 3 | NA | 0 | 4600 | 0 | NA | NA | NA | NA | NA | [47] |
44 | Soni et al. (2002) | 65 | M | 3 | 1, 3, 4, 7, 8 | 0 | 6000 | 0 | 0 | 0 | 0 | 25 | 25 | [48] |
45 | Strojan et al. (2002) | 65 | M | 1 | NA | 0 | 6000 | 0 | 0 | 0 | 1 | 93 | 93 | [49] |
46 | Strojan et al. (2002) | 72 | M | 2 | NA | 0 | 4600 | 0 | 0 | 0 | 1 | 56 | 56 | [49] |
47 | Strojan et al. (2002) | 50 | F | 1 | NA | 0 | 5000 | 0 | 0 | 0 | 0 | 27 | 27 | [49] |
48 | Maheshwari et al. (2001) | 65 | M | 3 | 3,4 | 0 | Y | 0 | 0 | 0 | 0 | 12 | 12 | [50] |
49 | Nagasaka et al. (2001) | 12 | F | 3 | 1,4 | 1 | 4320 | 0 | 0 | 0 | 0 | 48 | 48 | [51] |
50 | Abe et al. (2001) | 62 | F | NA | NA | 1 | 6500 | 0 | NA | NA | NA | NA | NA | [52] |
51 | Rakover et al. (2000) | 38 | M | 2 | 1, 5 | 1 | 5000 | 0 | 1 | 0 | 0 | 5 | 46 | [53] |
52 | Rosenblatt et al. (1999) | 40 | M | 2 | 1 | 0 | 5000 | 0 | 0 | 0 | 0 | 47 | 47 | [54] |
53 | Furukido et al. (1999) | 78 | F | 2 | NA | 1 | N | 0 | NA | NA | NA | NA | NA | [55] |
54 | Yusumatsu et al. (1999) | 77 | M | 1 | NA | 1 | 6000 | 0 | NA | NA | NA | NA | NA | [56] |
55 | Alexiou et al. (1999) | 69 | M | NA | NA | 1 | N | 0 | 0 | 0 | 0 | 62 | 62 | [57] |
56 | Alexiou et al. (1999) | 40 | M | 1 | NA | 1 | Y | 0 | 0 | 0 | 0 | 20 | 20 | [57] |
57 | Hotz et al. (1999) | 63 | M | NA | 4 | 1 | 4000 | 0 | 0 | 0 | 0 | 108 | 108 | [58] |
58 | Hotz et al. (1999) | 45 | M | NA | 7 | 1 | 5500 | 0 | NA | 0 | 0 | 108 | 108 | [58] |
59 | Nowak-Sadzikowska and Weiss (1998) | 34 | M | 1 | 1 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [59] |
60 | Nowak-Sadzikowska and Weiss (1998) | 50 | M | 2 | 1 | 0 | 6000 | 0 | 0 | 0 | 0 | 120 | 120 | [59] |
61 | Nowak-Sadzikowska and Weiss (1998) | 36 | M | 1 | 0 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [59] |
62 | Nowak-Sadzikowska and Weiss (1998) | 68 | F | 1 | 1 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [59] |
63 | Nowak-Sadzikowska and Weiss (1998) | 48 | M | 2 | 1 | 0 | 6000 | 0 | 0 | 0 | 0 | 120 | 120 | [59] |
64 | Weiss et al. (1998) | 34 | M | 1 | 1 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [60] |
65 | Weiss et al. (1998) | 50 | M | 2 | 1 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [60] |
66 | Weiss et al. (1998) | 36 | M | 1 | 0 | 0 | 6000 | 0 | 0 | 0 | 0 | 120 | 120 | [60] |
67 | Weiss et al. (1998) | 68 | F | 1 | 1 | 0 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [60] |
68 | Welsh et al. (1998) | 59 | M | 1 | 3,4 | 0 | 5000 | 0 | 0 | 0 | 0 | 42 | 42 | [61] |
69 | Bhattacharya et al. (1998) | 49 | F | 1 | 7,10 | 0 | NA | NA | 0 | 0 | 1 | 3 | 3 | [62] |
70 | Sulzner et al. (1998) | 49 | M | 1 | 3 | 0 | 4500 | 0 | 0 | 0 | 0 | 61 | 61 | [63] |
71 | Susnerwala et al. (1997) | 79 | F | NA | NA | 0 | 3500 | 0 | 0 | 0 | 0 | 132 | 132 | [64] |
72 | Susnerwala et al. (1997) | 65 | M | NA | NA | 0 | 4500 | 0 | 0 | 0 | 0 | 52 | 52 | [64] |
73 | Han et al. (1996) | 34 | M | 2 | NA | 1 | 5000 | 0 | NA | NA | NA | NA | NA | [65] |
74 | Rodriguez-de-Velasquez et al. (1996) | 33 | F | 5 | 2 | NA | NA | NA | NA | NA | NA | NA | NA | [66] |
75 | Abe et al. (1995) | 53 | F | 1 | NA | 0 | 4500 | 0 | NA | NA | NA | NA | NA | [67] |
76 | Narożny et al. (1995) | 51 | M | 1 | 1, 7, 10 | 0 | 6000 | 0 | 0 | 1 | 1 | 12 | 12 | [68] |
77 | Narożny et al. (1995) | 60 | M | 1 | 2, 4 | 1 | 5400 | 0 | 0 | 0 | 0 | 120 | 120 | [68] |
78 | Narożny et al. (1995) | 55 | F | 1 | 7 | 1 | N | 0 | 0 | 0 | 0 | 12 | 12 | [68] |
79 | Narożny et al. (1995) | 57 | M | 2 | 1 | 1 | N | 0 | 0 | 0 | 0 | 12 | 12 | [68] |
80 | Zbären and Zimmermann (1995) | 88 | M | 1 | 1, 3 | 1 | N | 0 | 0 | 0 | 0 | 72 | 72 | [69] |
81 | Zbären and Zimmermann (1995) | 71 | M | 1 | 1 | 1 | N | 0 | 0 | 0 | 0 | 12 | 12 | [69] |
82 | Rolins et al. (1995) | 43 | M | 1 | 0 | 0 | N | 0 | 0 | 0 | 0 | 36 | 36 | [70] |
83 | Mochimatsu et al. (1993) | 54 | M | 1 | NA | 1 | 5000 | 0 | NA | 1 | 0 | 144 | 144 | [71] |
84 | Weissmann et al. (1993) | 76 | M | 5 | 1, 3, 10 | 1 | Y | 0 | 0 | 0 | 0 | NA | NA | [72] |
85 | Jankowska-Kuc et al. (1993) | 58 | M | 4 | 1, 7 | 1 | 5950 | 0 | 0 | 0 | 0 | 36 | 36 | [73] |
86 | Barbu et al. (1992) | 69 | M | 1 | 2, 7 | 0 | Y | 0 | 0 | 0 | 0 | 36 | 36 | [74] |
87 | Tateno et al. (1990) | 54 | M | 1 | NA | 1 | N | 0 | NA | NA | NA | NA | NA | [75] |
88 | Kost (1990) | 43 | M | 6 | 1 | 1 | 7000 | 0 | 0 | 0 | NA | NA | 84 | [76] |
89 | Agatsuma et al. (1989) | 74 | M | 6 | NA | 1 | 4000 | 0 | NA | NA | NA | NA | NA | [77] |
90 | Gambino (1988) | 47 | M | 1 | 5, 7 | 1 | Y | 0 | NA | NA | 0 | NA | NA | [78] |
91 | Gaffney et al. (1987) | 80 | M | NA | NA | 0 | 4159 | 0 | 0 | 0 | 0 | 7 | 7 | [79] |
92 | Gadomski et al. (1986) | 54 | M | 2 | 1, 6, 7 | 1 | N | 1 | 0 | NA | 1 | 180 | 180 | [80] |
93 | Gadomski et al. (1986) | 51 | M | 1 | 1, 6, 7 | 0 | 4500 | 0 | 0 | NA | 0 | 60 | 60 | [80] |
94 | Burke et al. (1986) | 53 | M | 1 | 1, 3, 4 | 0 | N | 1 | 0 | 0 | 0 | 10 | 10 | [81] |
95 | Gormley et al. (1985) | 78 | F | 3 | 1, 4, 8 | 1 | 3250 | 0 | 0 | 0 | 0 | NA | NA | [82] |
96 | Maniglia and Xue (1983) | 64 | F | 5 | 1, 4 | 1 | 5000 | 0 | 0 | 0 | 1 | 12 | 12 | [83] |
97 | Ferlito et al. (1982) | 45 | M | 1 | 1 | 0 | N | 1 | 0 | 1 | 0 | 29 | 74 | [84] |
98 | Bjelkenkrantz et al. (1981) | NA | NA | 1 | NA | 1 | 5000 | 0 | 0 | 0 | 0 | 84 | 84 | [85] |
99 | Bush et al. (1981) | 52 | F | 1 | NA | 0 | 5500 | 0 | 0 | 0 | 1 | 36 | 36 | [86] |
100 | Bush et al. (1981) | 34 | F | NA | NA | 1 | 5500 | 0 | 0 | 0 | 0 | 42 | 42 | [86] |
101 | Endo et al. (1979) | 68 | M | 3 | NA | 0 | N | 1 | NA | NA | NA | NA | NA | [87] |
102 | Singh et al. (1979) | 42 | F | 1 | NA | 1 | Y | 0 | NA | 0 | NA | NA | 29 | [88] |
103 | Woodruff et al. (1979) | 64 | F | 1 | NA | 0 | Y | 0 | 0 | 0 | 1 | 72 | 72 | [89] |
104 | Woodruff et al. (1979) | 34 | F | 1 | NA | 0 | Y | 0 | 0 | 0 | 0 | NA | NA | [89] |
105 | Cohen et al. (1978) | 15 | F | 3 | 4 | 1 | 4000 | 0 | 1 | 0 | 0 | 3 | 22 | [90] |
106 | Pahor (1978) | 62 | M | 6 | 1, 4, 7 | 1 | 4500 | 1 | 1 | 0 | 0 | 21 | 31 | [91] |
107 | Gorenstein et al. (1977) | 58 | M | 4 | 1 | 1 | Y | 0 | NA | 0 | 0 | 36 | 36 | [92] |
108 | Gorenstein et al. (1977) | 63 | M | 4 | 1 | 1 | Y | 0 | NA | 0 | 0 | 300 | 300 | [92] |
109 | Gorenstein et al. (1977) | 59 | M | 3 | 4, 8 | 1 | N | 0 | NA | 0 | 1 | 60 | 60 | [92] |
110 | Gorenstein et al. (1977) | 42 | M | 2 | 1 | 1 | N | 0 | NA | 0 | 0 | 60 | 60 | [92] |
111 | Gorenstein et al. (1977) | 61 | M | 4 | 1, 7 | 0 | Y | 0 | NA | 0 | 0 | 72 | 72 | [92] |
112 | Petrovich et al. (1977) | 74 | M | 1 | 10 | 0 | 7312 | 0 | 0 | 0 | 0 | 24 | 88 | [93] |
113 | Muller and Fischer (1976) | 44 | M | 1 | 1, 8 | NA | NA | NA | NA | NA | NA | NA | NA | [94] |
114 | Horiuchi et al. (1973) | 51 | F | 1 | NA | 1 | N | 0 | NA | NA | NA | NA | NA | [95] |
115 | Booth et al. (1973) | 54 | F | 4 | NA | 1 | N | 0 | 1 | 0 | 1 | NA | 264 | [96] |
116 | Stone and Cole (1971) | 67 | M | 1 | NA | 0 | Y | 1 | 0 | 0 | 0 | 10 | 10 | [97] |
117 | Touma (1971) | 65 | M | 4 | NA | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [98] |
118 | Kakar et al. (1970) | 45 | F | 1 | 1, 4 | 1 | N | 0 | 0 | 0 | 0 | 13 | 13 | [99] |
119 | Poole and Marchetta (1968) | 41 | M | NA | NA | 1 | Y | 0 | NA | 0 | 1 | NA | 41 | [100] |
120 | Nabar (1968) | 60 | F | 1 | NA | 1 | N | 0 | 0 | 0 | 0 | 132 | 132 | [101] |
121 | Nabar (1968) | 55 | M | 1 | NA | 0 | Y | 0 | 0 | 0 | 1 | NA | NA | [101] |
122 | Nabar (1968) | 46 | F | 1 | NA | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [101] |
123 | Kraska (1967) | 40 | F | 1 | 1, 4 | 0 | 7290 | 0 | 0 | 0 | 0 | 14 | 14 | [102] |
124 | Studencki (1966) | 54 | F | 4 | 1, 4, 10 | 0 | 5500 | 0 | 0 | 0 | 0 | 7 | 7 | [103] |
125 | Todd (1965) | 65 | M | 1 | NA | 0 | 2500 | 0 | 1 | 1 | 1 | 60 | 96 | [104] |
126 | Todd (1965) | 43 | M | 1 | NA | 0 | 4800 | 0 | 0 | 0 | 0 | 60 | 60 | [104] |
127 | Webb et al. (1962) | 55 | F | 4 | 1 | 1 | N | 0 | 0 | 0 | 0 | 132 | 132 | [105] |
128 | Webb et al. (1962) | 32 | M | 3 | 1 | 1 | Y | 0 | 0 | 0 | 0 | 120 | 120 | [105] |
129 | Webb et al. (1962) | 46 | M | 1 | 1, 9 | 1 | Y | 0 | 1 | 1 | 1 | 168 | 330 | [105] |
130 | Krotz and Ritterhoff (1961) | 75 | M | NA | NA | 0 | Y | 0 | 1 | NA | 1 | NA | NA | [106] |
131 | Clark (1957) | 60 | F | 1 | 1, 4, 7 | 1 | N | 0 | 0 | 0 | 0 | 1 | 1 | [107] |
132 | Carson et al. (1955) | 52 | M | 1 | NA | 1 | Y | 0 | 0 | 1 | 0 | 54 | 54 | [108] |
133 | Carson et al. (1955) | 73 | M | 1 | NA | 1 | N | 0 | NA | NA | 1 | 156 | 156 | [108] |
134 | Korkis (1954) | 42 | F | 1 | NA | 1 | N | 0 | 0 | 0 | 0 | NA | NA | [109] |
135 | Priest (1952) | 50 | M | 4 | 2, 10 | 1 | N | 0 | 1 | 0 | 0 | 9 | 48 | [110] |
136 | Ewing and Foote (1952) | 76 | M | 1 | 1 | NA | Y | NA | 0 | 0 | 0 | 6 | 6 | [111] |
137 | Costen (1951) | 52 | M | 1 | NA | 0 | Y | 0 | 0 | 1 | 0 | NA | 12 | [112] |
138 | Mattick (1950) | 41 | M | 4 | 1, 3, 4, 7, 10 | 1 | N | 0 | 1 | 1 | 1 | 27 | 41 | [113] |
139 | Rawson et al. (1950) | 59 | F | 1 | NA | 1 | Y | 0 | 0 | 1 | 0 | 36 | NA | [114] |
140 | Stout and Kenney (1949) | 46 | M | 1 | 4, 6 | 1 | 8400 | 0 | 1 | 0 | 0 | 3 | 171 | [115] |
141 | Hodge and Wilson (1948) | 53 | M | 4 | 1, 3, 5, 10 | 1 | N | 0 | 0 | 0 | 0 | 12 | 12 | [116] |
142 | Lumb and Prossor (1948) | 34 | M | 3 | NA | 0 | Y | 0 | 1 | 0 | 0 | 24 | 30 | [117] |
143 | Lumb and Prossor (1948) | 20 | M | 7 | NA | 1 | Y | 0 | 0 | 0 | 0 | 90 | 90 | [117] |
144 | Clerf (1946) | 75 | M | 1 | NA | 1 | N | 0 | 0 | 0 | 1 | 13 | 13 | [118] |
145 | Jaeger (1942) | 67 | F | NA | NA | 0 | Y | 0 | 0 | 0 | 1 | 6 | 6 | [119] |
146 | Haven and Parkhill (1941) | 62 | M | 1 | NA | 1 | Y | 0 | 0 | 0 | 0 | 54 | 54 | [120] |
147 | Ringertz (1938) | 59 | M | 2 | 1 | 0 | Y | 0 | 0 | 0 | 0 | 48 | 48 | [121] |
148 | Ringertz (1938) | 73 | M | 1 | NA | 1 | N | 0 | 0 | 0 | 0 | 12 | 12 | [121] |
149 | Ringertz (1938) | 57 | F | 1 | NA | 1 | Y | 0 | 0 | 0 | 1 | 48 | 48 | [121] |
150 | Heindl (1933) | NA | NA | NA | NA | 1 | N | 0 | 0 | 0 | 0 | 36 | NA | [122] |
151 | Blacklock and Macartney (1932) | 64 | M | NA | NA | 1 | N | 0 | 0 | 0 | 0 | NA | 24 | [123] |
152 | Wachter (1914) | 48 | F | NA | NA | 1 | N | 0 | 0 | 0 | 0 | 5 | 142 | [124] |
NA—non-available data; y—years (age); mo—months; M—male; F—female; RTX—radiotherapy; CTH—chemotherapy; PCM—plasma cell myeloma; PFS—progression-free survival; OS—overall survival; Ref.—references; Localisation: 1—supraglottic, 2—glottic, 3—subglottic, 4—supraglottic + glottic, 5—glottic + subglottic, 6—supraglottic + glottic + subglottic, 7—supraglottic + subglottic; Symptoms: 0—no symptoms, 1—hoarseness, 2—dysphonia, 3—cough, 4—dyspnea, 5—globus sensation, 6—sore throat, 7—dysphagia, 8—stridor, 9—odynophagia, 10 —other; RTX: Y—non-available dose, N—no radiotherapy, NA—no information; Surgery/CTH/Local relapse/Progression to MM/Death: 1—yes, 0—no.